Full genome sequencing

1.2 Cellular DNA Damage responses, genomic instability. DNA is the blue print of life and all the information of life processes such as growth, metabolism, reproduction etc are encoded in the sequence of it. Therefore its very important to maintain the genomic integrity of this genetic material, not only to keep away defects in life processes but to pass a faithful information to the next progeny. Integrity of the DNA is usually challenged by both endogenous and exogenous agents who are capable…

DNA organization within cells is a complex and sophisticated process. This high level of complexity is due to the hundreds of thousands of interactions that can be enabled through organization. It is a known that promoter elements and enhancer elements work in unison to regulate gene expression. Often times enhancers are found hundreds of kilo-bases away from their interacting promoter elements. These enhancers initiate promoter activation via interactions amongst transcription factor binding…

1. INTRODUCTION Our mind comprises of 100 billion neurons and a trillion glia [1], which is a conservative structure of tissue measuring approx 3 lakes. The mind houses our mindfulness, our gathered encounters isolated and broke down and interpreted into a code by combined fleeting projections, and put away in a system including the working of cerebrum. Stroke has enhanced our present comprehension of the cerebrum more than some other ailment. There are numerous routes in which neurological…

The benefits and risks of the scientific method of genetically modifying crop species Since the emergence of agriculture over 10,000 years ago, humans have been altering the genomes of the crops they produce in order to increase the crop quality in many ways, with fruit size and palatability being two obvious examples. Whether this occurred incidentally through the techniques used to cultivate the plants or intentionally through artificial selection, humans have created strains of domesticated…

DNA analysis, also known as DNA profiling, testing, typing, is a process that takes genetic material and evaluates it so that it can identify individuals in a criminal investigation or in use of a forensic application. The beginning step of the performance of DNA analysis on a reference sample or person is the collection of DNA from cells. These cells can come from a blood sample or even swabbing the inside of an individual’s cheek. After it is collected, the samples are then sent to a lab for…

In particular, we are interested in understanding the PER gene in relationship to the free running period and the onset of activity in an organism. In addition, we will look to explain how multiple PER homologs arose in the human genome by identifying duplication events throughout…

These vectors contain a 4.7 kilobase DNA genome, and they are created by inserting the desired gene along with promoters and helper genes into the virus where the viral DNA would normally be found. Once the AAV reaches a target cell, the virus synthesizes a second strand of DNA to be paired with…

In the 1920s, A British researchers named Frederick Griffith studied bacterial pneumonia to find a vaccine for it. The specific bacteria was Streptococcus pneumoniae. Using streaking on a cultured Petri dish, the batterie was seperated into two strains, or colonies. The R-Strain was rough, and when injector into mice, it did not cause pneumonia, but the S-strain was smooth and slimy, and caused lethal pneumonia when injected. When the S-Strain was killed by heat, it did not cause sickness, but…

traits, gender, and abilities of their child. This kind of research is currently underway and is known as the Human Genome Project. The goal of the Human Genome Project is to understand each individual gene in the human body that makes a person unique and, in time, be able to allow parents to choose if their child is a boy or girl, if it has blue or brown eyes, etc. (The Human Genome Project). Is it right to be able to choose something that will decide the fate of someone besides yourself?…

these single gene mutations that are lethal, extremely dangerous, or unbearable to the human race. Harlequin ichthyosis, cystic fibrosis and Smith-Lemli-Opitz syndrome are all caused by single genes and can potentially be edited out of the human genome. Harlequin ichthyosis (HI) is a dangerous condition that is predominantly characterized by abnormal skin. Children with HI are born with very thick, hard skin that forms diamond patterns on the body. Between these diamonds of thick skin there…