Preliminary qualitative chemical tests show the presence of alkaloids, carbohydrates, saponins, steroids, terpenoids, phenolics, coumarins and fixed oil, etc.18 Desorption electrospray ionization was employed for fast and direct ambient detection of the anti-tumor drug, camptothecin, and its derivative, 9-methoxycamptothecin in Nothapodytes nimmoniana J. Graham. Different parts of the plant such as leaves, stems and bark were examined. The…
5-fluorodeoxyuridinemonophosphate that inhibits the DNA synthesis of the fungi Pharmacokinetic action: The drug is well absorbed in the gastrointestinal tract from 75% to 100%. Which means it should not be taken with food as it decreases the absorption of the drug. Resistance to flucytosine is commonly…
Synthesis and antibacterial activities of some Substituted 2-styrylquinolines Quinoline nucleus is present in many biologically active classes of compounds. Some of them are used as antiprotozoic, antibacterial and antifungal drugs [1]. Among the various classes of quinolines, 2-styryl quinolines form an important group having a wide spectrum of biological activities [2 – 8] including HIV integrase inhibition activity [9 - 15]. The general method for the synthesis of these derivatives is via…
DISCUSSION: Pseudomonas aeruginosa was selected to study their antimicrobial activity due to the production of pyocyanin, an antimicrobial phenazine pigment. For this study different clinical specimen were collected and from these P. aeruginosa was isolated. To isolate good pyocyanin producing P. aeruginosa, repeated plating of all the isolates on cetrimide agar helped in final selection of the 5 isolates. To examine the antimicrobial activity of those isolates, in vitro inhibition by cross…
Introduction: Resistance to antibiotics is an ongoing concern of the pharmaceutical industry. The limited number of antibiotics in the market to treat Gram negative bacteria made their resistance an issue that is being addressed worldwide. The isolation of colistin from Bacillus polymyxa var. colistinus in Japan in 1949 and the introduction of colistin into the market in 1959 as its inactive prodrug colistin methanesulfonate (CMS) were significant milestones in the treatment of this type of…
1. The organism that is the cause of this patient’s illness is Legionella pneumpohila, which means the patient has Legionnaire’s disease. Although there are other organisms that can cause similar diseases, it is clear that Legionella pneumpohila is the organism responsible for this patient’s disease. There are several reasons, but the one that stands out the most is that this organism can only grow on buffered charcoal-yeast extract, which is why there was no growth present on the 5% sheep blood…
Trench Mouth Trench mouth is a sudden (acute) infection that affects the gum tissue between your teeth (gingivitis). This infection quickly kills the gum tissue and causes painful sores (ulceration). Trench mouth causes very bad gum pain, very bad breath, and bleeding gums. The infection is not passed from person to person. CAUSES The mouth normally contains a balance of all the germs growing in it. An unhealthy mouth environment allows these bacteria to grow out of control, which upsets the…
The purpose of the infections caused by gram-positive cocci lab exercise is to utilize different identification and diagnostic techniques to differentiate various groups of bacteria, which cause infection. Our primary goal is first to establish the presence of an infection; then, determine which particular pathogens, or groups of pathogens, are the underlying cause of the infection. In the clinic, infections manifesting from gram-positive cocci are a common and growing problem. Two genera in…
Urinary Tract Infections “About 50% of women and 12% of men will have a urinary tract infection (UTI) at some time in their lives” (Richards, 2008).UTIs are the second particular type of infection. The bladder contains urine that is sterile. The urinary system compromise of the kidneys, ureters, bladder and urethra. The urinary system removes filtered liquid waste and urine. UTIs can occurs any area along the urinary tract. UTIs can be classified as lower and upper depending on the area of the…
Over the years farming practices have changed dramatically, and as a result many health complications have emerged. Because of the extreme transformations of agricultural practices, the health of animals, the environment, and more importantly humans have been put at risk. Today’s farming practices include feeding the livestock food they were not intended to eat corn and the remains of other animals. In contrast, farming in the 1700’s typically included animals eating grass (in which they were…