Formulations

The invention relates to formulation of Ketorolac Tromethamine and Phenylephrine Hydrochloride immediate release tablet having less disintegration time. HPLC method was developed and validated for determination of content of Ketorolac Tromethamine and Phenylephrine Hydrochloride in immediate release tablet. UV spectrophotometric method was developed and validated to study drug release profile of Ketorolac Tromethamine and Phenylephrine Hydrochloride in immediate release tablet. Background:…

Evaluation. Optimization of the formulations was done by selecting three process variables: a) concentration of soya lecithin b) concentration of surfactants (Sodium deoxycholate, Tween 80 and span80) and c)…

This essay aims to present a formulation of the categorical Imperative called the Humanity Formulation and deem it as a sufficient and plausible condition in determining moral worth. As a deontologist, Immanuel Kant believes that an action's moral worth is determined by the motive rather than the consequences it leads to and the focus of our moral actions should be on duty. This idea, called the categorical imperative, was a central and supreme concept of morality in Kantian ethics. The…

principle of morality that governs the rightness or wrongness of our actions, namely, the categorical imperative. In his written works, Kant brings forth his account of moral duty using the concept of the categorical imperative and its various formulations, claiming that the moral duty to help others in need follows from the categorical imperative. The formula of universal law, which urges us to “act on the basis of a maxim that could hold as a universal law (422),” argues that people should act…

right and wrong behaviors. Its first formulation is, “Act only according to that maxim by which you can at the same time will that it should become a universal law.” This first formulation simply acknowledges that you should only act by rules that would be widely accepted and followed. The second formulation is, “So act to treat humanity, whether in your own person or in that of any other, in every case as an end and never merely as a means.” This second formulation dives into the idea that…

econazole nanoparticles collected from nano-spray dryer were weighed and the yield was calculated by the following equation: % Yield=(Recovered mass)/(Mass entered in the spray dryer)×100 2.2.2.2. Determination of drug content The drug content of the formulations was determined by dissolving accurate amount of econazole nitrate nanoparticles in ethanol and the concentration of econazole nitrate was then measured at 271 nm by Shimadzu 1800 UV (Japan). All nanoparticles preparations were tested…

characteristics peaks of silymarin appear without any change in the spectrum of the drug. These results indicated that there was no interaction could be detected between the drug and the components of the base. Drug content Drug content of the prepared formulations was found to be ranged from 98.2 to 101.2% as showed in Table 2. These results indicated that complete distribution of the drug throughout the PLO gel base. Viscosity and Rheology…

6). The universalization formulation uses a logical test, in which we must inquire whether the performance of an action contradicts itself if everyone completes this action and this future action includes a statement called a maximum in which if it contradicts itself, the test fails…

seconds but it becomes moderately bitter (level 3) after 300 seconds. However, after taste masking the drug with β-cyclodextrin and aspartame, no bitter taste was observed. Stability studies After subjecting the formulation F9 for stability study, from the data, (Table 4) the formulation was found to be stable under the conditions mentioned before, since there was no significant change (p< 0.05) in physical form of tablets, changes in drug content, in vitro disintegration time and in…

Solubility studies The solubility of docetaxel in various vehicles selected as oil, surfactant and co-surfactant for formulation of L-SNEDDS was determined and presented in the Table 1. Among the tested vehicles, Capmul PG8 NF (>250 mg/mL), Capmul MCM C8 (>250 mg/mL) and Transcutol P (>200 mg/mL) had the highest drug solubilization capacity for docetaxel. Whereas, Captex and Gelucire 44/14 shown the least solubility of docetaxel in them. Based on the solubility results, Capmul PG8 NF…