Fever

C5086 Description: IC50: 100 nM, 12 and 60 µM for nNOS, eNOS, and iNOS, respectively Vinyl-L-NIO is a potent and selective inhibitor of nNOS. Nitric oxide synthase (NOS) catalyzes the NADPH- and O2-dependent conversion of L-arginine to nitric oxide (NO) and citrulline. Three isoforms including the neuronal (nNOS), endothelial, and inducible have currently been identified. Since NO overproduction is able to contribute to various pathophysiological conditions, NOS inhibitors are considered as…

When a person smokes, harmful chemicals within the tobacco are released into the body, causing damage to lung tissue, mucus glands and other parts of the respiratory system. The first time the person smokes, their lungs may repair themselves, but may fail to do so due to the continual use and intake of all these toxins which damages the cells and prevents them from repairing and regenerating. Smoking can cause many different types of respiratory diseases; two of which, are emphysema and chronic…

Overview Cystitis is a type of urinary tract infection that causes inflammation in the bladder. The infection is typically caused by bacteria that normally exist within the gastrointestinal tract. After stool is passed, some microorganisms continue to linger around the anus. Sometimes these bacteria make it to the bladder by passing through the urethra. Because they tend to thrive in the environment created by urine, it is not unusual for them to multiply quickly and cause an infection as they…

When measles are contracted a fever will first occur (“Measles”). Then a rash will break out, while the rash is present the fever may rise to temperatures of 104°F or higher (“Measles”). This disease is very easily transmitted it only takes a cough or sneeze for the virus to get into the air (“Measles”). Once the virus is in the…

infection that is caused by multiple herpes viruses. They can produce cold sores, genital inflammation or even conjunctivitis. There are two types of herpes simplex viruses, HSV-1 and HSV-2. HSV-1 is also known as oral herpes. It can cause cold sores and fever blisters around your mouth and/or on your face. HSV-1 is less contagious than . While as HSV-2 generally is responsible for genital herpes outbreaks. What is Zosters? Zosters is also known as shingles. Zoster is a painful…

Replication Inhibitors Replication inhibitors interfere with DNA synthesis. There are many of these inhibitors, but they typically work via two main mechanisms. One of these mechanisms involves either disrupting molecules that are needed for DNA polymerization or those needed in order to initiate replication. The other mechanism is by interfering with replication checkpoints that are involved in regulating the replication process. These checkpoints sometimes do this by triggering certain…

Town, South Africa on March 18th. His early childhood was spent hanging clothes at the family laundromat with his 2 older brothers. They had to provide for their mother so he quickly learnt what it meant to care for family. Unfortunately, he has hay fever. Shortly after his 11th birthday, his father was lucky enough to get a job for a large banking firm in America (Goliath National Bank). Everyone moved to the USA to start anew; his oldest brother, now graduated, became a Rabbi as the entire…

The 44-year-old obese female is admitted to the emergency room with fever, severe abdominal pain on the upper right side that radiates to the scapula and nausea. I believe this patient is experiencing acute cholecystitis, gallbladder attack. The signs and symptoms of acute cholecystitis includes: intense or sudden pain in the upper right part of the stomach, worsening pain with deep breathing extending to the lower part of the right shoulder blade, shortness of breath due to pain, nausea and…

ensuing violence, Dickens uses language such as “vast dusky mass (1)” , “forest of naked arms (5)”, and “ whirlpool of boiling waters (23)” to describe how people from all parts of Paris unified into one single mob, boiling over with “high-fever strain (20)” and “high-fever heat”. This effectively demonstrates that Dickens wanted to use this language to show…

yield will be calculated. Paracetamol (acetaminophen) is a pain reliever, a fever reducer and an anti-inflammatory drug so it is used in many other drugs. The exact mechanism of action of it is not known but the scheme of the synthesis of paracetamol can be seen below in Figure 1. This analgesic and antipyretic drug is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It can also relieve pain in mild arthritis. Paracetamol is an…