continuously turn on and off genes in response to external and internal environmental signals. The regulation of gene expression is especially important in multicellular organisms since it is essential for the different types of cell to have their own cell specialization (Campbell 365). In order for each cell to do it’s given role, they each need to maintain a program of gene expression individually to have some genes expressed and the rest not (Campbell 365). Only 20% of protein coding genes…
Proposed research: Aims and Objectives: Aim1: To address the roles of the Hira complex in rRNA transcription and embryonic development Aim2: To characterise rDNA chromatin organisation in the oocyte Aim3: To elucidate the transcriptional machinery of RNA Polymerase I in the oocyte Experimental Approach: Aim1: To address the roles of the Hira complex in rRNA transcription and embryonic development The Hira histone chaperone complex is an evolutionarily conserved complex, which is composed of…
explain hereditary traits that could not be elucidated by Mendel’s laws. Through extensive study of non-Mendelian inheritance, epigenesists developed a number of mechanisms for the alteration of gene expression that occurred outside of the actual DNA sequence. In addition, changes in the epigenetic expression of DNA have lead scientists to believe diseases, such as some cancers, have an epigenetic basis. Nevertheless, the implications of epigenetics were first categorized in the early twentieth…
defining features, neurons are heterogeneous in there gene expression, shape, and role in driving behavior (cite Zeisel et al. 2015 and Kamme et al 2003). Even within very homogenous populations such as the pyramidal CA1 neurons, there is significant variation in neuronal properties. This leads to the question of what is noise and what has a biological function? Eve Marder and colleagues eloquently demonstrated that gene expression changes we think are biologically relevant are often…
An Ancient Evil Since the beginning of time, censorship has harvested controversy. Leaders made laws that required the government to review all artwork and literature before releasing it to the public. During World War I, Congress passed the Espionage and Sedition Acts which implemented penalties for publishing or saying anything that may discourage our participation in the war and for criticizing the government. Another big example of censorship happened in Nazi Germany where they made efforts…
Louie Zamperini’s life was documented in the book Unbroken which was written by Laura Hillenbrand. It goes onto explain how Louie Silvie Zamperini was born on January 26, 1917 to Italian immigrants in Olean, New York at eleven and a half pounds he had black hair as coarse as barbed wire. His parents Anthony and Louise got married when she was sixteen and had Louie was she was eighteen. They lived in an apartment where only Italian was spoke and they called their boys Toots. As Louie became a…
“The introduction of genetically modified foods tampers with the essence of life in an experiment with an unknown outcome.” There are many who see genetically modified organisms (GMOs) as immoral and are skeptical about any positive side effects that might come from the cultivation of GMOs. This leads to the question of how we will feed our ever expanding population. By 2050 the world population will have grown well beyond nine billion, a giant increase from the 7 billion that are living now.…
The Act of Book Banning Should be Banned Have you ever wondered why books suddenly disappear from library shelves? The concept of libraries and school’s banning books is being openly opposed by Banned Books Week, a corporation that encourages the banning of books to be banned. Words have power and meaning and shouldn’t be tossed away or removed from shelves despite how mature or explicit they can be. According to Banned Books Week, “Banned Books Week was launched in 1982 in response to a sudden…
Figure 22. Relative mRNA expression in INS-1E cells after different chemicals treatment. Cells were treated with DHT, TCS and TCC for 48 h before RNA extraction for activity determination. Expression levels of the AR, pdx1, GK and Ins2 were determined by RT-QPCR and mRNA expression levels were normalized with TFIIB (A-D). DMSO treated samples were considered as control. Control samples were set as one and results are shown as mean ± S.E.M of duplicate samples from three independent experiments.…
Love is a motivation for people to fight, defend, and mature for. Lucius Apuleius' myth, Cupid and Psyche, tells the story of the strength and determination of the mortal needed to regain a lost love. Francesca Lia Block's modern retelling, Psyche's Dark Night, emphasizes the many issues that affect relationships and explores the pain that accompanies dating. The retelling offers a new look into love and whether or not it is worth all the pain that accompanies it. The updated setting and…