Excitotoxicity

INTRODUCTION The nervous systems are developed by the proliferation of progenitors in the epithelium, the specification of neurons and glia, the growth and guidance of axons and dendrites, and the development and refinement of electrical and chemical synapses. In the central nervous system (CNS), stem cells reside throughout life in the forebrain, continuing to generate neurons and glia in the subventricular zone (SVZ) surrounding the lateral ventricle and in the dentate gyrus of the…