Table 1 Composition of Lansoprazole microparticles Formulation code Amount of drug(mg) Amount of polymer chitosan (mg) Drug polymer Ratio Tween 80 (%w/v) F1 100 100 1:1 1.25 F2 100 200 1:2 1.25 F3 100 300 1:3 1.25 F4 100 400 1:4 1.25 F5 100 500 1:5 1.25 F6 100 600 1:6 1.25 Characterization of Lansoprazole microparticle The microparticle will be characterized for following parameters: Percentage yield: After complete drying, the drug loaded microparticle was collected and weighed accurately…
In pursuit of our continued interest in the development of solvent-free and green synthetic procedures, we decided to explore the use of tartaric acid catalyst for synthesis of polysubstituted quinolines via Friedlander condensation in high to excellent yields at 70 °C under solvent-free conditions. Initially the reaction between 2-aminobenzophenone (1.0 mmol) and dimedone (1.0 mmol), as the model reaction was examined in the presence varying amount of tartaric acid as catalyst and the results…
The instrumentation of a HPLC apparatus is as shown in the diagram above. A HPLC apparatus is including a solvent reservoir, degasser, pump, injector, HPLC column, detector and data collection device. Solvent reservoir The solvent reservoir is usually a glassware or reagent bottle which contained the analytic sample. It is located at the upper part of the HPLC. It is also known as mobile phase reservoir since the sample will be moved. The flowing of the sample is depends on gravitational…
3.1. Chemical composition and monosaccharide analysis Polysaccharide molecules are linked together by water molecules through hydrogen bonds in an aqueous solution. Adding ethanol into aqueous solution of polysaccharide initially dehydrate polysaccharides, enhance intra-molecular hydrogen bonding, cause conformational change and aggregation of polysaccharide molecules, and eventually leads to the precipitation of macromolecular chains, and the following addition of alcohol solvent gradually…
Since 1984 the legal age to drink alcohol is 21 years old. The National Minimum drinking age act prohibited people under 21 in the United States to drink alcohol. Before 1984 the legal drinking age was 18 years old. There are many pros and cons to lowering the drinking age. Alcohol poisoning, drunk driving accidents, and stupid actions while being drunk happen to 18 year olds and 21 year olds the same even with the drinking again being 21. Some pros of the minimum drinking age being lowered…
Pharmacology 1 Major Assignment Salbutamol The chemical name of salbutamol is 1-(4-hydroxy-3-hydroxymethylphenyl)-2-(t-butylamino)-ethanol sulphate, chemical structure is (C13H21NO3)2 • H2SO4 and molecular weight is 576.7g/mol Generic Name: albuterol Commonly used brand name(s): Available doses and dosage forms: Oral salbutamol: Adults and Children over 12 years: Usual starting dosage of salbutamol is 2mg or 4 mg 3 or 4 times a day. A dosage exceeding 4 milligrams of salbutamol 4 times…
Sterile Saline (0.9% w/v NaCl) Dissolve 9.0gm of NaCl in 1000ml water and dispense 9.0ml of the solution into 20ml test tubes. Autoclave the tubes as per the validated cycle and cool to room temperature. Sterile saline with polysorbate 80: Dissolve 9.0gm of NaCl in 1000ml water and add .5gm of tween 80 to the resulting saline solution, dispense 9.0 ml of the solution into a number of 20ml test tubes. Autoclave the tubes Preparation of Inoculums and its Standardization: 1) Take loop full of…
Gasmalla et al Trop J Pharm Res, January 2014;13 (1): 61 Tropical Journal of Pharmaceutical Research January 2014; 13 (1): 61-65 ISSN: 1596-5996 (print); 1596-9827 (electronic) © Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. All rights reserved. Available online at http://www.tjpr.org http://dx.doi.org/10.4314/tjpr.v13i1.9 Original Research Article Nutritional Composition of Stevia rebaudiana Bertoni Leaf: Effect of Drying Method Mohammed Abdalbasit…
1 Introduction Berberine (BBR), an isoquinoline alkaloid (Fig. 1), is isolated from many medicinal herbs, such as Coptidis rhizome (Coptis chinensis Franch.) and Cortex phellodendri (Phellodendron chinense C.K.Schneid.) (1). BBR has been used to treat microbial infection, diarrhea, and other gastrointestinal (GI) diseases due to its antibacterial, antidiarrheal and strong antidotal properties (2, 3). In recent years, much focus has been put on its other potential bioactivities, such as…
FTIR analysis of the stem bark extracts of Cassia fistula has absorption bands and the wave numbers (cm-1) of the prominent peaks obtained were described in Table 2. The peak at a frequency of 3463 cm-1, 1618 cm-1, 1448.3 cm-1 and 1241.9 cm-1 were strong while the others vary from medium to weak. Discussion: Phytochemical studies revealed the presence of secondary metabolites like tannins, flavonoid, carbohydrate, saponins, glycosides and phenol in the leaf extract while tannins, flavonoids,…