As a chemical engineer for a large chemical manufacturer I developed an excel tool that analyzed sales trends for our products and compared the sales history to trends in customer requests for those products. This tool identified markets and applications where customers were asking for information about products but they were not placing orders. I hypothesized that by analyzing these gaps we could discover when our customers were evaluating our product for a potential new application. This would…
Molecular Basis of Wolman Disease Wolman disease is an autosomal recessive condition that is characterized as the complete deficiency of the lysosomal enzyme, lysosomal acid lipase (LAL).1 LAL is responsible for hydrolyzing triglycerides and cholesterol esters in the body that have been internalized via receptor mediated endocytosis.2,3 Therefore this enzyme functions inside the lysosome to carry out hydrolysis of lipids. Wolman disease is contracted by an estimated 1 out of 350,000 newborn…
the structure of HBA.. Presence of ester group in the HBA backbone due to the reaction…
In this experiment, the competing enantioselective conversion (CEC) method was used to react an unknown secondary alcohol, which is either the R- or the S- enantiomer, with S-HBTM and R-HBTM separately. Thin-layer chromatography (TLC) was used to determine which reaction was faster. If the S-HBTM was faster, then the unknown secondary alcohol had the R configuration. If the R-HBTM was faster, then the unknown secondary alcohol had the S configuration. 1H NMR was used to determine the molecular…
ship back to America. His wife is shocked by how large of a ring he had bought for her. Not only that, but Mrs. Ester and her son will go on a cruise to Hawaii that Sr. had planned for them. He includes in a note that the reason he is giving them all this is, because he will not make it home by the holidays, as he must resume his duties as an ambassador. As Christmas gets even nearer, Ester Sr. buys his family more flowers at the University Club…
(freeze-dryer). Synthesizing "PYRET-5" molecules "PYRET-5" (refer to Scheme 1 for structure) was the target molecule to be synthesized by replacing one of the –OH groups with 1-pyrenehexanoic which would be connected by either an ester or an amide group. Both compounds, the ester and the amide, were synthesized with the pyrene as the limiting…
using leaf, skin, fruit and fruit puree. The first publication was made on the volatile components of guava in 1970. The compounds from guava fruit were extracted using distillation. Twenty-two compounds were present in the oil: eight alcohols, six esters, three aldehydes four terpenes, one ketone and an alcohol. Hexanol and cis-3- hexen-1-ol were higher in concentrations as compared to other six alcohols. It was concluded that combination of methyl benzoate, β-phenyl ethyl acetate, methyl…
Metin GUMUS et al.,[1]. In this study, hazelnut (Corylus avellana L.) kernel oil was tested and studied as an alternative fuel in diesel engines. The hazelnut kernel oil is made to undergo transesterfication process for reducing the viscosity of the oil. The processed hazelnut kernel oil possesses all the properties of biodiesel used in the diesel engine. The suitable transesterification reaction conditions for hazelnut kernel oil are volumetric ratio of the reactants in the ratio 1:5, reaction…
politically for instance, Cesar Chavez used her image, during the Mexican War for Independence her image was used as well. The image of La Virgen has evolved throughout time racing religious, cultural, gender and racial consciousness. Artist like Ester Hernandez and Alma Lopez tend to alter and portray the image of La Virgen into their artwork. However, in a more “liberal “way since women are always portray or…
of NHS with O-acylisourea results in the formation of NHS-ester, which is more reactive towards primary amines and more resistant to hydrolysis, and it also undergoes minimal formation of N-acylurea [40]. Therefore, NHS is usually used with EDC to increase the efficiency of EDC-mediated enzyme immobilization. The formation of NHS-ester is critically affected by pH; the carboxyl groups have poor reactivity to EDC/NHS at pH <4.5, and NHS-esters are more susceptible to hydrolysis at alkaline pH…