Ester

Vinorelbine also known as Navelbine® is an anti-cancer chemotherapy drug. It belongs to a class of chemotherapy drugs called vinca-alkaloids; which can be categorised as spindle poisons1. Vinorelbine and Vindesine are semi-synthetic derivatives from the first generation of vinca-alkaloids; Vinblastine and Vincristine2. These original vinca-alkaloids were derived from dried leaves of the Madagascan periwinkle (vinca rosea) plant1. Madagascar periwinkle is also used in the treatment for diabetes,…

We’re running away again, in the middle of the nigh, this time accompanied by Daniel, in an aged truck loaded with hens and rabbits for sale at the Issoire’s market. We made our journey, hidden together with Prince between the rabbit cages covered by a canvas. Before the dawn arrived at a bridge at Issoire’s entry, and the truck driver left us there. Daniel told to us that would need to walk at least two hours up to come to our refuge, a castle lost in this remote area. It did not dawn yet when…

New York University professor Ester Buchholz references psychoanalyst and pediatrician Donald Woods Winnicott when addressing this need for solitude in mental health treatment, “In almost all our psychoanalytic treatments, there come times when the ability to be alone is important to…

CHAPTER 4 RESULTS AND DISCUSSION 4.1 Incomplete Carbon Glucose Preparation for sulfonated solid acid catalyst must undergo a process which is called carbonization or pyrolysis. Glucose is natural organic compounds had been used as starting raw material because it is cheap and less toxic. Carbonization is an important step before the sulfonation process because it will form amorphous carbon composed of small carbon sheets [B] and produced sites for sulfonic group to be attached or…

into three main groups (Seymour, 2002) (30). Polygalacturonase (PGase) and pectate lyase (PLase) (EC 4.2.2.2) split the molecular chains of the respective polymers (Kashyap et al., 2001) (29). Pectin methyl esterase (PME) (EC 3.1.11) hydrolyzes the ester linkage between carboxyl and methyl groups of pectin and release methanol. Endopolygalacturonase (EC3.2.1.15) and exo-polygalacturonase (EC 3.2.1.67) are the enzymes of particular interest to industry because they act on pectin, hydrolyzing its…

Smith Road Bridge #03.730 - Tech 21Bridge. This seemingly small, inconspicuous bridge near the City of Hamilton / Ross and St. Clair Township lines has turned into the center of national media consideration. The Butler County Engineer's Office has put up a structure built entirely of advanced composite materials originally designed for use in the industry of aerospace - filaments, for example, glass implanted in epoxy. The bridge, renamed the Tech 21 Bridge, was dedicated on 25 of July 1997 and…

In The Great Gatsby, Tom Buchanan mentions racial fears and anxieties going on during the modernist period when talking to Nick Caraway. He says, “Civilization’s going to pieces…the white race will be utterly submerged. It’s all scientific stuff; it’s been proved”. Scientific discoveries during the early part of the modernist period were against the mixing of races because African Americans were viewed as biologically inferior to whites. Some believed that racial inferiority was not based on…

which has four binding sites for biotin or biotinylated derivatives with extraordinary affinity. Biotin can be chemically coupled to a binder molecule (e.g., a protein, DNA, hormone, etc.) without disturbing the interaction with its target molecule by a procedure called biotinylation. Avidin can then be exploited to “sandwich” between the biotinylated binder and a targeting molecule or probe. Avidin was also coupled with a functional moiety in some cases. Through the avidin-biotin system, we can…

Beta Alanine Beta Alanine is a dietary supplement that is designed to mimic the action of the non-essential amino acid alanine that is produced naturally in the healthy body. The body to produce proteins uses amino acids. The body uses alanine to convert sugar to energy and eliminate toxins from the body. Beta alanine is the manufactured nutritional performance supplement that helps the body produce more energy and eliminate fatigue experienced by athletes. This synthetic form of amino acid is…

Fear and corruption run rampant during one of America’s darkest periods. 1692 in Salem, Massachusetts was a time of fear, allegation, and distress. The town of Salem will forever be linked to the witch trials and the executions of innocent victims. One person tortured to death, five others die in prison, and nineteen men and women hanged (6). The atmosphere surrounding Salem was ripe for the occasion. Some of the predominant causes of the Trials were a combination of the strict Puritan codes…