Monocistronic mRNA Coupled transcription-translation possible Not possible Linearly polyribosome Circular polyribosome No cap on mRNa 5’end of mRNa recognized by the cap Start codon is next AUG after ribosome biding site No ribosome binding site First amino acid is formyl-Met First Met is unmodified 70S ribosomes (30S and 50S subunit) 80S (40S and 60S) Small 30S : 16S rRNA and 21 proteins Small 40S : 18S rRNA and 33 proteins Large 50S: 23S and 5S rRNA plus 31 protein Large 60S : 28S, 5.8S and…
Introduction Nucleotide is a building block for deoxyribose nucleic acids which is called DNA that has four base units,adenin(A) ,thymine(T) ,guanine(G), cytosine(C). The nucleotides can bond with their base pairs(A=T,G=C) to form a linear strand that is supported by sugar-phosphate backbone. In the linear strand, some of three base sequence is a codon and each codon is related to an amino acid. These codons come together in a linear sequence and create a gene. Gene can be called as cipher that…
Result and Discussions 3.1. Changes in catalytic pocket Instead of having the conventional catalytic triad residues (His665, His667 and Asp767) in it’s protease domain, Lon protease employs the Ser679 – Lys722 catalytic dyad to form a catalytic pocket for promoting proteolysis. But the mutations in catalytic dyad residues make some changes in the catalytic pocket of these three mutant types. A comparison of SASA values and RSA values [Supplementary file 1] were done among the catalytic…
Amino acids Amino acids are building block s of proteins. Each amino acid contains main three structural components. 1) Amino group 2) Carboxcilic group 3) R group Figure 1 https://www.bing.com/images/search?q=amino+acids&view=detailv2&&id=072990A13D7C6B29926E0FC3F9E9BE59C8A6322E 2016 R can be hydrogen or any other functional group .in world there are around 182-200 found to be present in nature but we can find 20 aminoacids in…
4.3. The third dsRBD of Xlrbpa (xl3) is a protein/protein dimerization domain The strongest interacting partner from a two-hybrid screen with Xlrbpa turned out to be Xlrbpa itself. Two-hybrid assays with deletion constructs together with coimmunoprecipitation experiments identified xl3 but neither xl1 nor xl2 as a dimerization domain (Fig. 18, 19 and 20). Xl3 enhances the PKR antagonistic ability of Xlrbpa as previously indicated and discussed. The third domains of PACT and RAX, the human and…
Introduction Osteogenesis imperfecta describes a group of genetic disorders that are colloquially known as “brittle bone disease” and is estimated to affect around 7 out 100,000 people around the world. As the name suggests osteogenesis imperfecta is characterized by imperfect formation of the bones that leads to frequent fractures or breaks from minor trauma (Rauch et al., 2004). Depending on the severity of symptoms the impact to an affected individual 's life can differ. This paper will…
shape? This experiment is going to test which additives make gelatin stronger. In learning about this project, there were many new terms in the sources used. Some of them will be discussed in this paper (gelatin, collagen, protein, tensile force, amino acid, triple helix, collagen fiber, and tensile strength). Gelatin is a protein food gotten by adding water to collagen, the most common animal protein. (Jiggle it:…
and, in general, are not reversible except by further chemical reactions. A polymer is a large molecule, or macromolecule, composed of many repeated subunits. Because of their broad range of properties, both synthetic and natural polymers play an essential and ubiquitous role in everyday life. Polymers range from familiar synthetic plastics such as polystyrene to natural biopolymers such as DNA and proteins that are fundamental to biological structure and function.…
In a biochemical reaction, enzyme which are proteins based compounds are used as a catalyst to produce a high yields. Proteins are the macromolecular components of almost enzymes, except for ribozymes, a class of RNA modifying catalysts. Enzymes are classified on the basis of their composition; simple enzymes are those composed wholly of proteins, whereas, complex enzymes which also known as haloenzymes, composed of protein plus a relatively small organic molecule. In this terminology the…
through the hair follicle and towards the surface of your scalp, it is known as keratinization. Keratin is rich in sulfur protein. Most of your hair is made of proteins (amino acids). Amino acids are made up of theses elements; Carbon, Oxygen, Hydrogen, Nitrogen and Sulfur also known as side bonds.These elements help link the amino acids together and…