Epinephrine

A drug that was introduced in 1987 that helps with allergic reactions; by giving you a dose of epinephrine. The drug floated around until it landed in the hands of Mylan in May 2007. Since then they have lobbied and successfully got a law passed called the "School Access to Emergency Epinephrine Act." Which forces schools to purchase the drug. Therefore, if something may occur on school grounds there is an EpiPen available and you won 't have…

over the epinephrine auto-injector market”, said Maryland Democrat Elijah Cummings and Jason Chaffetz, a Utah Republican who chairs the House Committee on Oversight and Government Reform.…

Pheochromocytomas are neural crest-derived tumors that produce catecholamines (such as epinephrine and norepinephrine) and arise mainly from the adrenal gland. Closely affiliated tumors of extra-adrenal paraganglia are also known as extra-adrenal pheochromocytomas. All these functional chromaffin tumors can result in substantial morbidity and mortality due to catecholamine oversecretion. Pheochromocytoma can have exceptionally variable clinical presentations - from rare and escalating…

Despite the fact that a majority of serial killers are men there is always an exception. Kristen Gilbert is that exception, born on November 13, 1967 in Fall River, Massachusetts, this little known serial killer was crafty, clever, and immune to the feeling of true remorse. Kristen Gilbert was described as a social butterfly that thrived at her job, academics, and most aspects of life and to be labeled as a serial killer came as a surprise to most of her co-workers. In this report I will outline…

Anderson gives us the example of the messenger being epinephrine mainly affecting liver cells; epinephrine will dock to the G-protein because epinephrine is a ligand and they cannot go through the hydrophobic region of the membrane leading to the conformation shape change in the protein this releases alpha subunits that will be added to the enzyme. Adenylyl…

life-threatening parasitic infection, was increased to $750 from $13.50, by the drug company the Turing Pharmaceuticals (Pollack, 2015). Another pharmaceutical company Mylan recently increased the price of EpiPen, the epinephrine auto-injector more than 500 percent than the price in 2007. The epinephrine auto-injector called EpiPen and EpiPen Jr, are intended for immediate administration…

Americans who need to buy from a brand that has essentially monopolized the market of a certain medicine. For instance, over the past eight years, the price of a commonly used medical device, the EpiPen, has been steadily increasing. The EpiPen is an epinephrine auto-injector used to treat severe allergic reactions and anaphylactic shock (Varandani); anaphylactic shock is “a severe, potentially life-threatening allergic reaction that occurs within seconds or minutes of exposure to an allergen”…

demand due to families taking drastic measures to compensate for the price surge. Since Mylan acquired the EpiPen in 2007, the cost to purchase the medicine has increase from $100 for a pack of two to $600 for the same amount (Ramsey, L. 2016). Epinephrine, the drug that is in the EpiPen, costs about $1 a dose. It’s the delivery system that demands the outrageous price hike. EpiPen’s main competitor, Auvi-Q, competed with Mylan to see who could charge the highest price for the same product.…

neurotransmitters such as epinephrine and norepinephrine, as well as catecholamines (VanMeter & Hubert, 2014, p. 423). According to a research article written by Eric Grouzmann (2015), “In chromaffin cells and pheochromocytes, norepinephrine (NE) and epinephrine (E) are stored in vesicles where they sustain a passive leakage into the cytoplasm before being recaptured in the vesicle pool” (p.2). This is important because, the enzyme responsible for transforming norepinephrine into epinephrine is…

Auvi-Q, an auto-injector epinephrine product now produced by Kaleo Pharmaceuticals (formerly produced by Sanofi) will be placed on the market sometime in 2017. They have yet to set a price, but most people believe they will only be a few dollars cheaper than the EpiPen (Arstechnica)…