Epigenetics

The theory of psychosocial development, proposed by Erik Erikson, stresses the idea of continuous growth met with several identity crises influenced by the social environment. According to Erikson, humans are constantly developing and changing throughout their lives, not only in a physical sense but also personality wise. These life developments vary on the age of the person and can be determined through the eight psychosocial stages defined by Erikson. Each stage involves a crisis which can…

homeostasis and ultrastructures of hippocampal neurons. In relation to the amino acid neurotransmission, report reveal that arsenic-induced excessive glutamate accumulation in the extracellular space induces excitotoxicity [29]. Arsenic exposure can alter epigenetic regulations and the signaling of hypothalamus-pituitary-adrenal axis (HPA). However, in the present study arsenic was not able to manifest any significant alteration in the DNA laddering pattern in cerebral cortex and cerebellum…

The bearing of abuse leaves deep emotional scars--the child never learns how to deal with true life pressures. Life stressors that may lead the battered to become the batterer. In the book, “Loving Your Child to Much”, it explains that emotional intelligence is attained by “…teaching children how to deal with anger, disappointment, fear, excitement, and the other emotions we all experience in life” (Clinton & Sibcy, 2006, p170). Sexual abuse does not show external physical signs, but there are…

This shows Onychonycteris finneyi, a bat fossil. The image shows its wing digits widely spread out with small claws on tip of each finger. It also shows the long tail found in earlier bat fossils (Moskowitz, 2008). Molecular Mechanisms The origins of bats wing muscles, molecular and cellular mechanisms are unknown but this research shows that the wing muscles of bats come from “a multiple myogenic source of different embryonic origins” (Tokita, Abe, && Suzuki, 2012). The results conclude that…

teenager is spending their time with because some experiment with sexual actives faster then other groups or cliques. The first experience of sexual contact during this stage is called autoerotic behavior. This is usually done in the high school years and is from a conversation or curiosity of what others are doing or talking about doing. Teenagers feel many emotions at this transition. They feel anxious, confused, pressured, and even worried. This generation of teenagers is having more…

KRAS: So far three human Ras genes have been identified. Actually Ras homolog to the oncogene from Kristen Ras Sarcoma (KRAS). HRas homologous to the oncogene from Harvey Rat Sarcoma virus(HRAS) and NRas first isolated from the human neuroblastoma. These three different Ras genes are highly homologous but functionally different. However the degree of redundancy remains topic of investigation (Pylayeva-Gupta et al. 2011). Ras are central mediators of downstream of growth factor receptor…

Antecedents of frailty According to Walker & Avant (2005), antecedents of a concept are events which have to take place before a concept occurs. From the literature reviewed, the antecedents of frail older adults include cellular and molecular changes, individualization and cumulative factors, system dysregulations and system impairments as described below: Cellular and Molecular Changes: at this level accumulating cellular and molecular destruction becomes decisive, because the processes of…

Aim 3. Validation of transcriptional drivers and therapeutic combinations in CRPC. Rationale and strategy: To experimentally validate computationally predicted drivers of CRPC, we will use loss- and gain-of-function approaches for in vitro (i.e., cell lines) and in vivo (i.e., xenograft models) experimental validation to determine whether these genes are essential for drug-resistance. Computationally inferred drug combinations will be validated for their effect on MRs’ activity and ability to…

Post-Traumatic Stress Disorder in Veterans Post-Traumatic Stress Disorder (PTSD) is the name for the psychiatric disorder that has been around since the beginning of the human species, but has not been widely researched until recently. PTSD occurs after someone has experienced a traumatic event such as life threat, serious injury, or death. This is not the case for every person that has experienced a traumatic event, though. According to the National Center for PTSD (2015), the APA introduced…

Obesity, diabetes, depression, suicide thoughts and attempts, hypertension, and cancer. While daylight savings time, or DST, might seem harmless, and even beneficial, it can cause all the problems listed above. Daylight savings time should be abolished, as DST can ruin schedules, for an important meeting, it can be more dangerous, increasing the rate of traffic accidents, causing sleep deprivation, and a multitude of other issues, already listed above. DST ruins schedules, and that could be…