Effective dose

note that it normally takes more than one dose to save a user’s life. Sometimes up to 10 doses to completely reverse all effects. Morgan Lentes a reporter for WLKY news stated that, “In a year’s time Metro EMS spent more than $187,000 on naloxone. In September alone, metro EMS made 613 overdose runs and used naloxone in 235 of these cases.” Money is being funded to emergency response teams to spend on Narcan when this money could be spent in much more effective ways. Kristen Kennedy with WKYT…

similar area under the curve (AUC). Its distributive properties include low plasma protein binding (30%) and a volume of distribution of about 3.4 L/kg. Dose adjustments should be made in patients with renal function impairment because elimination of desvenlafaxine is significantly correlated with creatinine clearance. The recommended maximum dose of desvenlafaxine is 100 mg/day for moderate to severe hepatic impairment because there is minor metabolism by the liver via CYP3A4. The approximate…

Pharmacist code of ethics I found the code of ethics for Pharmacists online at http://www.pharmacist.com/code-ethics. I think the code level is practical and it is very obvious that the 8 codes are achieved most of the time through diligent effort. For example: one code of the codes states “A pharmacist seeks justice in the distribution of health resources”, it reveals that being honest and fair is a code for living before being a code for pharmacists. I know the pharmacists too would wish to be…

One option is to lower the dose for patients who demonstrate similar efficacy at a lower dose. Another option would be to shorten the length of the treatment for individuals in cases where a shorter treatment would not pose any harm (Rosoff). These alternative plans still require physician’s to make careful decisions…

Medication reconciliation must be completed by a nurse, physician or pharmacist on admission and discharge to avoid medication discrepancies. Perform medication reconciliation on every patient and if the patient is unsure of the medications they take then contact their caregivers or their pharmacy to obtain an accurate list. Then teach patients how to manage their own medications. Recommend pill boxes or charts for those with memory impairments. Enlist spouses and children to help ensure…

FEV1 is the important determinant of the respiratory health in COPD patients. The researchers found no significant effects on FEV1 whether the single dose therapy (change in FEV1, −5.28% [CI, −10.03% to −0.54%]) or continued therapy (change in FEV1, 1.07% [CI, −3.3% to 5.44%]) was initiated in the mild to moderate airway disease.2 Similar study analysis which evaluated FEV1 response in the patients with…

No dose of Tylenol is going to ease your arthritis pain — no matter what your doctor tells you. [Dr. Al Sears Health Tips] It's important to know the benefits and risks associated with each medication to determine which ones are right for you. (Photo via Dr. Al Sears) And a team of researchers from the University of Bern, in Switzerland, has just proved it. The researchers gathered data from 74 randomized trials involving 58,500 patients. And what they discovered was that acetaminophen —…

patient’s needs. While knowing this she prioritized herself to visit the first patient as to be free up later when the surgeon visits the patient. The nurse’s top priority for the day included assessing her patients, checking documentations for next dose of medications, and provides comfort and safety to her patients. After prioritizing which patient the nurse would see first and when medications were due, she introduced herself to the first patient and preformed an assessment. The nurse…

Introduction Doxorubicin, an anthracycline antibiotic, is commonly used as an effective antineoplastic agent, in the treatment of various of malignancies, including leukemia, lymphoma, and solid tumors. Unfortunately, the clinical use of this drug is limited by cumulative dose-dependent cardiotoxicity, which may cause irreversible and severe effect of cardiomyopathy [1] The specific mechanisms of doxorubicin (DOX) induced cardiotoxicity are complex and although decades of research on this drug,…

responsible for marijuana’s “high.” It can take over an hour to take effect, whereas smoked marijuana is effective almost immediately. Patients who suffer from nausea also have trouble keeping pills down. It is also reported that the dosage is hard to control and may not have any effect on the patient taking the pill. In addition, the cost of Marinol can cost three to five times more than a comparable dose of medical…