EC 1.11.1

Hans Zellweger, a Swiss American professor of pediatrics and genetics at the University of Iowa in the mid-1960s described the familial disorder among siblings that was later named after him for the recognition of his discovery, the Zellweger Syndrome. Peroxisomes are cell structures that break down toxic substances and synthesize lipids (fatty acids, oils, and waxes) that are needed for cell function. Peroxisomes are what is needed for normal brain development and its function and it’s what forms the myelin cover which is the substance that coats nerve fibers. Nerve fibers are very thin, thread-like transmission lines that basically carry signals. Responsible for delivering signals and sensations from the nerves to various parts of the human body, such as in the skin, muscles, and internal organs. Now, any one of the 13 genes, termed PEX gene with a defect is a diseased called Zellweger Syndrome. The genes are required for normal formation and function of peroxisome. Peroxisomes are also required in the human body for normal eye, liver, kidney and bone functions. Zellweger syndrome is one of a group of four diseases related and referred to as Peroxisome Biogenesis Disorders (PBD). Toxic molecules that enter the person’s bloodstream fail to be detoxified because of a lack of peroxisome even though there are mechanisms for detoxification. The organic creation of peroxisome plays an important role that’s related to different chemical reactions in a person’s body. Each gene…

Created in 1968 and running until 2016, Zap Comix was a ground-breaking and defying comic book that defied convention and societal law (Comic Code) it became a model for the Comix movement. A comic that has evolved with the ages taking a progressive and often regressive stance on ‘hot topics’ of the time. In Zap Comix Issue 1 Crumb describes himself as a ‘raving lunatic’ through the use of self-caricatures in this case; Flakey Foont and Mr. Natural. Showing from the get-go Crumb wasn’t one to…