Drosophila

Proof reading and Mismatch repair are crucial processes in DNA replication, their existence reduces the likelihood of a mutation occurring by a significant amount. In fact, proofreading reduces the likelihood of errors occurring to approximately one in every ten million nucleotides (Pierce, 2012-pp354). This essay will emphasise the importance of proofreading during, and mismatch repair post DNA replication and explore its significance in the mechanisms that drive Lynch syndrome. In eukaryotes 3…

Lysosomes are one of the abounding organelles that make up a typical eukaryotic cell. A typical human cell contains hundreds of lysosomes but can be found in much higher quantities in cells more directly involved in exocytosis and cells of the immune system. Under a microscope, lysosomes can be observed as spherical-shaped, tiny membranous sacs composed of a single phospholipid bilayer that separates the acidic interior (pH 4.8-5) from the rest of the cell. The acidity is maintained by the…

Originally it was believed that all traits are blended together. Due to the work of Gregor Mendel, though, it was shown that characteristics are a result of inherited factors, known as genes1. Genes are units of heredity on a chromosome that bring about our existence and create diversity. This diversity arises from the fact that there are different forms of genes known as alleles. All the alleles of an organism are referred to as that organism’s genotype and results in an organism’s phenotype,…

I believe that it is possible for human life to be meaningful. I have this way of thinking because embracing our values can bring meaning to our lives, if we truly embrace them (Rachels, 2012, p. 173). Having personal relationships that are meaningful can also add a sense of happiness to our lives. There is nothing more worthwhile then having people that reciprocate your love. Therefore, family and friends are essential. In addition to this, a meaningful life can be one in which you are proud…

This research uses Drosophila as a model organism, where a panel of flies will be infected by Sigma Virus and separated based on the extent of susceptibility. A GWAS (Genome Wide Association Study) analysis is then employed to specify genetic variants in particular genes responsible…

Food, Festive Events and Colors always make people think of and connect to laughers, happiness and joy. Once there is a saying “You can’t buy happiness, but you can buy ice cream. And that’s kind of the SAME THING!” The Odyssey of Feast showcases the joyful moments created by food and beverages in the 17th century with wide ranges of Still Life and Dutch Golden Age paintings. If you are looking for some Still-Life and Dutch Golden Age paintings, or you perceive yourself as a foodie. The Odyssey…

Creating food: Before making the food, make sure to wash your hands thoroughly. After washing your hands, make sure to wipe down your station before using it. There are alcohol spray bottles throughout the lab. Spray it in your area and use the paper towels to wipe it down. Obtain a clean polystyrene vial and fill one eighth of the tube with dry food. The fly food was purchased from the Carolina Biological Supply company. Add about 9 ml of water to the dry food and gently roll the vial five…

Saibhuvaneswari RA1611014010048 JUMPING GENES Transposable elements (TEs), also known as "jumping genes" or transposons, are sequences of DNA that move (or jump) from one location in the genome to another. A transposable element (TE or transposon) is a DNA sequence that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and genome size. Transposition often results in duplication of the TE. The transposable elements make…

neurons in vitro (Wang 2011). Mutant, GFP-Htt protein was also observed in TNTs in vitro, transferring between primary CGN, suggesting a role for TNT mediated spread of Huntington’s in the brain (Costanzo 2013). In vivo, TNTs have been observed in drosophila and between dendritic cells in mouse cornea (Knopik-Skrocka 2014). It is plausible that TNTs play a role in PD since TNTs are involved in various neurodegenerative disorders, and α-synuclein has been observed in TNTs…

Did research on what males and females look like. We observed the frozen flies. On the first week we used fly nap as an anesthetic for the flies and waiting for them to fall asleep. We sexed the flies and put 10 male and 10 female into a tube. We provided them with food and a sponge to allow oxygen to flow in and out of the tube. The males were Wild type and the Females were type C. After one week we came back to several pupa larva and parents that were active. We once again sedated them with…