Donepezil

Aricept is a medication, which can help to decrease the symptoms of Alzheimer’s disease by increasing the level of chemical in the brain called acetylcholine messenger (Health Canada, 2015). Medication does not treat Alzheimer’s disease; however, it helps patients to progress their thinking, memory and the capability to do their simple everyday jobs, which reduces the signs of Alzheimer’s disease (Aricept, 2016). Aricept is a medication that helps to stabilize dementia that is associated with Alzheimer’s disease (Health Canada, 2015). The Generic Name, of this drug is entitled Donepezil Hydrochloride and the brand name is Aricept and Aricept RDT (Rexall, 2016). This tablet has three different colors, which is associated to its dose. The strength…

The methoxy groups and the ketone group give the molecule a surface anionic charge which helps in binding to the target site. Indanone ring provides metabolic stability to the compound and so donepezil has a longer half-life. Physical properties: Donepezil is mainly given in its hydrochloride form. It is a white crystalline powder and is freely soluble in chloroform and soluble in…

Some of the major pharmaceuticals that are used today include donepezil, galantamine, memantine and rivastigmine. Of these, galantamine is one of the most commonly prescribed and used. Research published in Psychopharmacology examined the effects that galantamine had on patients with Alzheimer 's disease and concluded that people treated with galantamine have improved cognitive function ( Ellis et al, 2009). This is because galantamine enhances cholinergic function by restricting…

agonists are the group of drugs that are prescribed for the treatment of Alzheimer’s disease. They work by reversibly blocking acetylcholinesterase at the synaptic cleft. This blocking allows the accumulation of ACh released from the nerve endings and leads to increased and prolonged stimulation of ACh receptor sites at all of the postsynaptic cholinergic sites (Karch, 2013). These indirect-acting cholinergic agonists cross the blood-brain barrier and mostly affect the cells in the cortex to…

The 4 drugs so far are donepezil, galantamine, memantine and rivastigmine. Donepezil and memantine may be used in combination to treat Alzheimer’s (Alzheimer’s Disease & Dementia). Alzheimer’s destroys synapses and kills neurons. Drugs for Alzheimer’s support the communication process of neurons by helping maintain the synapse and also tries to keep neurons from dying. Cholinesterase inhibitors slow down the process that breaks down the neurotransmitter acetylcholine. Donepezil, galantamine, and…

nonpharmacological treatments appropriately, and assessing patient / family motivation to include volunteer for a clinical trial. Counselors must document if the patient is being treated for cognitive symptoms, behavioral and psychological, and / or alternative treatment. I would suggest to counselors to know what medications are being used, and what stage of Alzheimer’s the medication is assisting the patient. Along with knowing what medications are approved by the U.S. Food and Drug…

Alzheimer’s disease can surely only be diagnosed after death, by the autopsy of brain to check brain cells. But when the patient is alive, the test by neurologists consists of studying the signs and symptoms of the individual to check for memory loss, changes in behavior. Treatment of Alzheimer’s Disease The patients of Alzheimer’s need the help of a neurologist as well as a therapist. Both medication and therapy is required. There are three drugs for Alzheimer’s disease. They are donepezil…

and to control movement. (Association) My other aunt is currently going through this stage. She currently lives in China and is taken care of by her son. She can’t control her ability of when she needs to use the restroom, no longer is able to control her movement and doesn’t communicate understandable words. This is one of the most difficult things my family has gone through. My aunt was a mother figure to my mom. Its hard to see my mom so upset and feel helpless in this type of situation.…

makes it more probable for the patient to have vivid hallucinations due to the L-Dopa treatment that is given to patients to help them with their thinking. Patients are now given donepezil which is to help with the hallucinations and doctors have seen that there is a decline in a person 's hallucinations and improvement in cognition. Here is a case study done on a 79 year old man that was found by police wandering around in the middle of nowhere and confused on where he was and what he was…

Alzheimer’s disease is a multifactorial, progressive, fatal neurodegenerative disorder characterized by loss of cholinergic neurons in the hippocampus and the cerebral cortex, mainly affecting cholinergic neurotransmission. There are three pathophysiological factors involved in neuronal death: hyperphosphorylation of tau protein and consequent disruption of the cellular cytoskeleton, extracellular deposition of beta amyloid and neuroinflammation. Progressively, there is a reduction in the…