DNA sequencing

Darwin’s Theory of normal choice was known as a hereditary change in a populace coming about because of differential conceptive achievement. Darwin had persuaded the vast majority of mainstream researchers that new species emerge through plunge through change in a spreading example of difference from regular precursors, however while most researchers acknowledged that normal choice is a legitimate and experimentally testable speculation, Darwin's view that it is the essential instrument of…

Andrew Read is an evolutionary biologist. When he was young, he used work with native’s birds of New Zealand, which is his homeland. Working with birds, he began to question about how these natives birds lives longer then humans so he became an evolutionary biologist. So now, he works with malaria parasite. These parasites bread very rapidly as if they are on drugs. Therefore, Mr. Read is worried about these bugs. In the 1960, the United States surgeon General believed that we have won the war…

Biopharmaceutics This is the in-vivo or in-vitro study of various physiochemical factors including developmental and design factors affecting the rate and extent of drug absorption with regards to the pharmacological effect of the drug. Biopharmaceutical studies use this result to improve likely problems that could arise from poor drug absorption and increase the bioavailability of newly formulated drugs. The main purpose of biopharmaceutical studies is to increase, monitor and maintain the rate…

Firstname Lastname Instructor’s Name Course Number Date Genetically modified canola: Agronomic benefits and environmental disadvantages The world’s food source is facing selection and sustainability pressures from unpredictable climatic changes, massive growth in population and continuous reduction in agricultural land (Nicolia et al. 77). Genetically modified (GM) crops seem to be the solution to feeding billions of people, although their negative long-term impacts are still a heavily debated…

identify genes that gives rise to phenotypic effects when they are switched off, and also helps to analyze the effects of these genes in cells or complete organisms. The first step in the gene trap process is to integrate an artificially constricted DNA into a genome of a cell line, usually an embryonic stem (ES) cell line. To carry out this…

Plasminogen Activator Inhibitor-1(PAI-1)4G/5G polymorphism with oxidative stress markers Malondialdehyde (MDA) and High sensitivity C-reactive protein (hs-CRP), fibrinolysis marker PAI-1and lipid profiles. Subject and Methods: Blood was drawn and DNA extracted from 90 subjects (46 cases and 44 controls). The 4G/5G polymorphism of PAI-1 was amplified using specific primers. Amplified products were visualized by staining with Ethidium bromide after electrophoresis in agarose. Risk factors PAI-1,…

Chemistry: Enasidenib is a first in class, a selective allosteric inhibitor of mutant isocitrate dehydrogenase-2 (IDH2) inhibitor discovered at Agios Pharmaceutical, Inc. in the United States of America. Recently, on 1 August 2017, Celgene Corporation and Agios Pharmaceutical in cooperation won the approval for Enasidenib under brand name IdhifaTm for the treatment of relapsed/refractory acute myeloid leukemia. it is a white to off-white crystalline, non hygroscopic powder existing in…

The fungi Alternaria is a phyto-pathogen cause leaf blight disease to variety of plants. Alternaria alternata and Alternaria helianthi was isolated from Dalbergia sissoo L. and Helianthus annuus L. respectively. Test antagonists grow faster than the pathogen and produced inhibition zones thereby limiting the growth of the pathogen. These antagonistic interactions influence the incidence and severity of the disease caused by the pathogen. When the two Alternaria spp. were tested by dual culture…

A case on cancer cell By Shamik D. Majumdar What does cancer cell mean? Normal cells can repair themselves if any part gets damaged . This process is known as DNA repair. If the damage is too bad, they will self slaughter- known as apoptosis. (1) The molecules in cancer cells decide whether a cell should repair itself or not .EX: “a protein called p53 normally checks to see if the genes can be repaired or whether the cell should die”, so basically it…

Wide hybridization and characterization of hybrids of Linum usitatissimum L. for crossability, various agro-morphological traits and rust resistance Nimit Kumar*, Satish Paul, H.K. Chaudhary, Navdeep S. Jamwal and Amaninder Deep Singh Department of Crop Improvement, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur-176062, India For correspondence: nk.kakran@gmail.com SHORT SUMMARY: The present research has yielded a wide array of germplasm which will serve as a potential source of…