DNA profiling

Guanine, Adenine, Thymine, Cytosine are the four nucleotide bases of DNA. The clever title, of the futuristic movie revolving around genetic engineering, “Gattaca”, is a DNA sequence. The symbolism, as within the title, continues throughout the thought provoking film. DNA is like the instructions used to develop life. However, in the film, DNA is also a prime determinate of social class. Vincent Freeman is a baby of faith, conceived by means of natural reproduction. His parent’s decision, to…

Contrary to people believe, DNA evidence are available in fewer than 10 percent of violent crimes. These cases are typically rape and murder cases, where it is more likely the offender will leave skin tissue or bodily fluids that will yield DNA. More than 90 percent of the persons exonerated by DNA evidence were convicted of rape, murder, or both. DNA evidence is often available in these crimes of violence unless the perpetrator takes measures to remove all hair, semen, blood, and other bodily…

For example, I performed gene expression profiling in the developing thalamus of Gbx2-deficient transgenic mice using DNA microarray and elucidated the genetic cascade directing the embryonic thalamus development. I have published a number of papers in highly ranked peer-reviewed journals in this regard. Before pursuing biomedical…

carries a gene from a different species, called transgenic. Genetic engineering can also be referred to as cross-breeding or gene-swapping. In 1953, Francis Crick and James Watson discovered the structure for the chemical molecule, Deoxyribonucleic acid. DNA is a substance that carries genetic information in the cells of plants and animals, and occurs in the nuclei of all living cells. A genetically modified organism (GMO), is an organism whose genome has been modified by genetic engineering.…

babies, or build-a-baby, are typically thought of in context of science fiction, but the possible technology used create them already exist. Preimplantation genetic diagnosis (PGD), created in 1989, was one of the first iterations of a genetic profiling technology that could literally allow people to ‘design’ their offspring. It works in tandem with in-vitro fertilization (IVF), since fertilization in a laboratory after egg retrieval is needed in order to be able to evaluate the embryo before…

CHAPTER-2 VARIABILITY AMONG THE ALTERNARIA BRASSICAE ISOLATES INTRODUCTION The chapter is mainly concerned with examining the variability among Alternaria brassicae isolates from the oilseed brassicas. Since, the oilseed brassicas are more prone to the fungal attack and thereby, resulting in reduced productivity of the oilseed. Therefore, the present investigation focuses on the studying the features such as morphological, pathological and molecular variability of Alternaria brassicae. The…

Background Basal cell carcinoma can be defined as a malignant neoplasm in humans. Basal cell carcinoma originates in the areas between the follicles, subject to a spontaneous mutation. BCC’s can be organized into four categories: nodular, morpheaform, metatypical, and superficial. BCC can be treated generally through SMO inhibitors, for example, vismodegib (Ximena 398). Vismodegib is a molecule inhibitor of the Hedgehog (Hh) pathway (Pricl 389). The pathogenesis of BCC is the inapposite…

Foremost, the accuracy of any technologies used to identify, collect, and/or analyse evidence has a major impact on the outcome of a case. If a piece of evidence is improperly analysed, such as a contaminated DNA sample, then an individual could be wrongly accused. To avoid this as much as possible, only the most relevant and accurate of forensic technologies should be used. The techniques that are less accurate should merely be used as an extension of the data…

Firearms team, the coroner, and the trace evidence team that deals with fingerprinting, impressions, etc. These teams used scientific knowledge and or tools to prove that the evidence did or did not put Bryan Bridges at the scene of the crime and that he did or did not commit the murder. In this case they all found that he was guilty and therefore the court can trust that he is guilty and convict Bridges. Bryan Bridges is a Hispanic/Caucasian male who stands at 5’07” and 170 pounds. His date of…

Each person has their own unique DNA that makes them different from others. The scientists had invented the DNA analysis procedures which helps to bring down the criminals due to the DNA that they left behind the scene. These techniques are collecting the DNA specimen and extracting DNA from the specimen. In addition, other areas such as immunohistochemistry (IHC) and forensic chemistry also help the investigators to complete their jobs. DNA analysis is also used to prove the relationship…