DNA methylation

The Effects of Technology on Biomedicine Dontae Weatherly CRN: Submitted [date and time] The Effects of Technology on Biomedicine INTRODUCTION Biomedicine is a branch of medical sciences that ties biology and clinical practice together. Biomedicine or medical biology is a major facet of modern health care and lab diagnostics. Biomedicine and biotechnology go hand in hand, with that being said, technology has a great impact on the advancement of biomedicine.…

severe distortions in the conformation of DNA at the mismatch site occurs. The clamp has numerous hydrophobic and charged residues, which is consistent with a role in dimerizing with the charged residues of the clamp of MSH6. In addition, it may work to stabilize the highly unfavorable state of DNA when a mismatch is recognized. The positively charged residues such as lysine and arginine can form ion pairs with the negatively charged phosphate groups on the DNA backbone. Furthermore, the…

Recombination and mutation are the motivation of evolution. Recombination is critical for repairing DNA lesions and for chromosomal pairing, and exchange during meiosis (Krejci et al. 2012). Recombination does not occur uniformly on the chromosomes of eukaryotes. Meiotic recombination in well studied yeast revealed that non-uniformity of recombination was observed when the frame of reference is an entire chromosome, multigene region and a pair of genes or a small region upstream of a gene…

They are here. Knock. Knock. The heavy taps stir me and move me to organize my papers. Two hunched over adults enter with somber and nervous expressions. It is the first meeting with my new clients: Angela and Joseph, parents of a two-year-old girl named Annie. They witnessed their daughter go through a seizure. As a parent myself, I can imagine the pain and stress they are suffering now. “Her name is Annie. She had a seizure last Saturday” said Angela, a petite woman in a shaky voice. Her…

In recent years MTHFR has been popularised in social media and blogs with various levels of information and potential misinformation. A search on google.com.au using the term “MTHFR” provided 1,330,000 results in 0.40 seconds.[1] With all of this different information being available 24 hours per day, all year round, it can be confusing for practitioners and patients to sift through to determine what is scientific, clinical or “hearsay”. 5,10-methylenetetrahydrofolate reductase (MTHFR)…

forensic science, and everyday there are advancements. Law enforcement officers and forensic technicians have many tools they can work with now, making it a bit easier to help them solve crimes. They have tools for fingerprint analysis, ballistics, DNA typing, and recently forensic phenotyping of simple physical traits such as human eye and hair color. The future of forensic science is bright; tools, gadgets and programs are ever evolving and forensic technicians have taken the advantage to…

The rare disease known as Hutchinson-Gilford Progeria Syndrome (HGPS) is a genetic disorder that causes newborn children to age more rapidly than normal. HGPS belongs to a group of progeroid syndromes that can classified as segmental disorder that affect many tissues and organs and display symptoms that resemble physiological aging. This disorder unfortunately results in a short life span for those affected. It is reported that it occurs about 1 in 8 million births around the globe. (Arancio,…

wonder if DNA is the most effect way to catching a criminal (Steen). Without the use of it there would not be the freeing or those accused of a crime and proving of their innocence. In today’s society the use of deoxyribonucleic acid, known as DNA; is the basic building block of life and has aided in identifying criminals and solving major crimes (Houck and Siegel). But on the other hand DNA has also proven many individuals to be innocent of a crime. The information that inside of one’s DNA set…

Genetic Engineering (GE) is the process of altering the genetic makeup of an organism by extracting certain genes from the donor organism and inserting them into the genome of the recipient organism (“What”). Genes are small segments consisting of DNA…

Most of us never think about the food we eat. How is it made? Where does it come from? What exactly is in it? Is it safe to eat? Sometimes the best answer to those questions is no answer at all. Some of us may not even care, some will. It’s all about the perspective of the person. No answer is wrong. In the book The Botany of Desire, Michael Pollan writes about a potato called the NewLeaf. The NewLeaf potato isn’t like any other kind of ordinary potato. It’s a genetically engineered potato that…