Disseminated intravascular coagulation

“Disseminated intravascular coagulation (DIC) is a life-threatening acquired pathologic process in which the clotting system is abnormally activated, resulting in widespread clot formation in the small vessels throughout the body. The pathophysiology is excess thrombin is generated, followed by deposition of fibrin strands in the body tissues.” (Ball, 2012) “The circulating fibrin fragments later begin to interfere with platelet aggregation and other aspects of the clotting mechanism, resulting in bleeding or hemorrhage.” (Lewis, 2014). DIC can be acute or chronic, most people think it’s only acute. Signs and symptoms of disseminated intravascular coagulation depend whether it’s acute or chronic. Acute DIC develops quickly and is very life…

This series of events leads to intravascular thrombosis, where micro clots form in the smaller blood vessels, causing further inadequate perfusion and worsening of ischaemia. These clots form widespread purpura fulminans, best described as the tiny blood spots and discoloration of the skin in patients infected with the meningococcal bacteria (Heyderman, 1993). As these micro clots form, clotting factors become exhausted leading to thrombocytopenia. With a reduced amount of platelets and clotting…

face shows optimism and hope for the future. "It's been a passion of many years for me working with vets and on veterans issues," he said. "This is a culminating year of all those struggles." Riley served for 20 years with the U.S. Army and Coast Guard. He was serving as a rescue swimmer in 1997 when he became ill while on vacation. "I drove down to Dauphin Island in my RV, and soon as I opened the door this wind hit me," he said. "I felt as if I was going to die." Riley said he was "black…

trauma (multiple falls), and recent major livery surgery (Schwartz & Rote, 2014, p. 1048-1050). Patients who are in their advanced ages are at risk in developing a VTE due to slower blood flow in their veins (Schwartz & Rote, 2014, p. 1048). Additionally, malignancy, trauma and post-operative state are examples of secondary or acquired hypercoagulability, which places individuals at risk for forming a VTE (Schwartz & Rote, 2014, p. 1049-1050). Moreover, one of Mrs. X’s surgeries was an extended…

receive a diagnosis on whether they have hemophilia A or B and if that hemophilia is mild, moderate or severe. This is an important step in management because there are types of hemophilia that are treated differently. Those with hemophilia A are distinguished by the insufficient amount of factor VIII (FVIII), while those with hemophilia B lack sufficient amounts of factor IX (FIX) (Anderson et al. 2013). There are a few methodologies that are used to treat the various types of hemophilia, but…

thrombus can form when there is damage in the lining of a blood vessel, either in an artery or a vein (MedicineNet, 2015). In addition, clots occur when the blood stops circulating, becomes idle, or in diseases that result in abnormal blood clotting. There are times when a thrombus will form when it is not needed and can potentially lead to significant consequences. Damages can be greatly obvious, but at times other times, they are difficult to detect. Poor clotting with a minor injury to a…

This paper is scribed to present the compare and contrast between chronic venous insufficiency and deep venous thromboses. It will also present pathophysiology and treatment of the two mentioned diseases. The symptoms to the diseases may be identical although the anatomy is truly different.There is no exact amount of the people that are affected by chronic venous insufficiency and deep vein thrombosis although the estimated range is from 300,000 to over 600,000 each year in the United States.…

Von Willebrand Disease Von Willebrand disease is the most common bleeding disorder. It occurs when the body makes too little of the von Willebrand factor (VWF), a protein that helps blood clot, or when the VWF is misshapen and does not work the way it should. VWF is a carrier for another protein, called factor 8, that helps blood clot. When VWF levels are low or when VWF is not working properly, factor 8 levels are low as well and the body is less able to form stable blood clots. There are…

Hemophilia is a genetic disease that affects the blood. There are two types of this disease, they are classified as Hemophilia A and Hemophilia B. This genetic disease is most commonly found in males, although, the gene is passed down from the mother, the “carrier.” However, it has been discovered that hemophilia can occur in females, though it is rare. Hemophilia A is the classic type of this disorder where the affected individuals have a profound deficiency in Factor VIII, a part of your…

prolonged bleeding. These individuals are diagnosed before they are five or six years old. However, they also may not be diagnosed until later in life. Hemophilia is caused by a defect in one of the genes that determine how the body makes blood clotting factor VIII or IX. Hemophilia A is caused by mutations in the FVIII which allows for proteins called coagulation factor VIII. While hemophilia B are from mutations in FIX that produces coagulation factor IX. Coagulation factors are proteins that…