Derivatives

Deoxyribonucleic acid consists of a phosphate and deoxyribose backbone, and four different nitrogenous bases. These bases are adenine, guanine, cytosine, and thymine. Ribonucleic acid, the molecule formed in the transcription of DNA, is made up of phosphate, ribose, and adenine, guanine, cytosine, and uracil. The backbone of DNA consists of a phosphate bonded to a deoxyribose molecule. Deoxyribose is a sugar containing five carbons, and it is called deoxyribose as it is missing an oxygen atom on…

leucine to proline at amino acid position 1544(Ashcroft, 2005). This mutation simply reduce the activation of the channel by stimulatory nucleotide MgADP, as the NBDs sensitivity to this nucleotide is greatly/entirely lost. The failure of the channel activation means the open state of the channel pore is greatly reduced/blocked. This occurs as the inhibitory nucleotide (ATP) would have higher affinity for the channel than the activating nucleotide (MgADP). Closure of the K+ channel leads to…

The Effectiveness of Bacteria Killing Agents Bacteria are everywhere, you may not be able to see it, but it is present. Many different bacteria killing agents exist. For example, there are antibiotics, which can be helpful, but harmful, and are usually prescribed by doctors. Some people also use essential oils whish are safer and healthier. Bacteria can be good and bad. Good bacteria help to keep you healthy. The bad bacteria can make you sick. Poor diets and constipation can lead to bad…

Maple Syrup Urine Disease (MSUD) is a rare, autosomal recessive metabolic disorder in which the body is unable to process certain amino acids properly. It causes brain damage and progressive nervous system degeneration. MSUD is caused by mutations in three different genes: BCKDHA, BCKDHB and DBT (Warrell, Cox and Firth, 2012). The BCKDHA gene causes MSUD Type Ia due to the mutation in the E1α subunit, BCKDHB causes Type Ib due to the mutation in the E1ᵦ subunit, and DBT causes Type II due to…

10 years later and that castle still sits on my shelf. Even though I don't have those medieval adventures anymore, it still serves as an advisor for my adventure through high school: The adventures through the continuous function to defeat the derivative and rescue the beautiful tangent equation while holding my ground against the stress-typhoon of finding a Homecoming date. Even with multiple failures, I did not give up, instead, I took apart the 1000 steps to compute slope using the difference…

The embodied state: The embodied state is the long-term trajectory of society member’s internal emotions and attitudes (Bourdieu, 2011). Embodiment is a process in which a member of society internalises the social energy around them and then externalises it in a reproduction of culture. It is a cumulative process in which many factors attribute to the embodied state (Bourdieu, 2011). The embodiment of cultural capital really derives from the reproduction by the society of the habits and…

solvent many main group organometallic compounds form bridged compounds in which alkyl is bridging between metal atoms.7 Organometallic compounds of transition metals: During 1950s the proper study of organo derivatives of transition metals begin whereas the non- transition metal organo derivatives has been studied for more than hundred years before that of transition metals. The structure of organometallic compound of transition metals looks very similar to the coordination compounds in…

Caterpillar and the Global Financial Crisis Despite being a multinational corporation (MNC) and the global leader in the manufacturing of construction equipment, mining equipment, engines (diesel, natural gas), turbines, and locomotives, Caterpillar (CAT), like other global leaders, was susceptible to adverse effects cause by the global credit crisis of 2009 (CAT, 2016). As such, the company’s exposure to risks associated with conducting business overseas were exacerbated by deficiencies in the…

insulin sensitizing agents can increase ovulation rates in some women with PCOS. Metformin has been used widely for that purpose. Aromatase Inhibitors Anastrozole and letrozole are triazole derivatives that act as potent, competitive, nonsteroidal inhibitors of aromatase. Aromatase is an enzyme which catalyzes the rate-limiting step in estrogen production. Letrozole inhibits estrogen production in the hypothalamus–pituitary axis, which results in compensatory increase in gonadotropin-releasing…

as a prescription medication in the U.S, however this remains very unlikely. Bolasterone is a fairly potent anabolic steroid, measured in human subjects to have approximately twice the anabolic effect of methandrostenolone. Despite being a derivative of testosterone, bolasterone is considerably more anabolic than it is androgenic in nature. Bodybuilders and athletes would often use this drug in bulking cycle, where adding extra weight wasn't a concern. Bolasterone is a very estrogenic…