Deletion

Homeobox, also known as HOX genes, are genes that determine organ and limb formation during early embryonic development. Frances R. Goodman writes in his article “Limb Malformations and the Human HOX Genes” that humans have 39 HOX genes which are organized into four clusters. They have their own roles in the development of the central nervous system, axial skeleton, genitalia, and limbs. The study of HOX genes can lead to the identities of a number of human malformations. According to Shane C.…

Likewise, in Shakespeare’s play, Macbeth, the word “hail” is used twelve times when referring to Macbeth, the protagonist. However, Macbeth is only hailed before he commits the sinful acts of murder mentioned in the play. Shakespeare’s intentional deletion of the word “hail” in regards to Macbeth reveals how human instinct causes individuals to become alienated from society as consequence for their immoral actions. Shakespeare exposes this quality of the human condition through the lack of…

This syndrome has physical, behavioral and developmental characteristics, and is caused by a deletion in chromosome 17 (PRISMS). Common characteristics of this syndrome are developmental delay, different levels of intellectual disability, early speech/language delay, high pain tolerance, chronic sleep disturbances, hugging, attention problems, tantrums…

An American geneticist, Hermann J. Muller, was the first to discover the existence of telomere in 1938. He was irradiating Drosophila melanogaster with X-ray to produce mutation at the Drosophila’s chromosomal ends and he observed no mutants with deletions or inversions during the experiment (Muller, 1938). He suggested the presence of a protective cap, known as telomere, at the chromosomal end. It wasn’t a year later; Barbara McClintock - a cytogeneticist from the University of Cornell -…

based on their method of analysis (Hybridization-based molecular markers or PCR-based molecular markers). Molecular markers are also used to detect the genomic structure of different organisms, genotypic variations such as insertions, mutations, deletions and single nucleotide polymorphisms, genome organization and evolutions (Jones et al., 2009). In many crop breeding programmes, these markers are used to track loci and genomic regions which are strongly linked with a large number of agronomic…

The Party in 1984, by George Orwell, represents an oligarchy, which has eliminated the fundamental characteristics of a democratic society. Through sheer determination of the Party and its unlimited omnipotent power, human spirit is crushed in the eradication of privacy, individuality, and freedom. These though, are the risks associated with totalitarianism. “Totalitarianism is a form of government that theoretically permits no individual freedom and that seeks to subordinate all aspects of…

classes often explore the histories of the living or, more famously put, the winners. However, many American history courses fail to mention the effects of settler colonialism on racialized groups, specifically the Native Americans, resulting in the deletion of their existence and stories. Through her memoir Bad Indians, Deborah Miranda thoroughly brings forth the continuous oppression and experiences of Native Americans by revising the version of U.S. history that many are taught with her…

Personalized Medicine In recent years, the growth and changes in medicine has been exponential than linear. With the innovations of new cutting edge technologies, medicine is not only changing through technological perspective but through human perspective as well. While millions of lives have been saved with the traditional one –size-fits-all blockbuster medicine, some drawbacks are still preventing an effective treatment for each individual. An individual’s response to any medications are…

Scope of the project • Branch : Fort • Transactions : RTGS/NEFT, Internal Fund Transfer, FDR Opening Request, FDR Premature withdrawal, Net Banking Transaction/ Activation, Static Data Updation ( Change of Company Name, Address Change, Addition/ Deletion of Authorised Signatory) • Analysis: Customer Interface, Difference between Corporate, retail and Insignia Customers) 2.3 Problem Statement Deviations from the standard operating procedures of Financial and Non-Financial transactions at…

synthesized DNA strands can serve as template in the next cycle. 4.2. Advantages of Multiplex Polymerase Chain Reaction Since its first description in 1988, multiplex PCR has been successfully applied in many areas of DNA testing including analyses of deletion, mutations, and polymorphisms, or quantitative assays and reverse transcription (Henegariu et al., 1997). Indeed, this technique has several advantages such as increasing the number of genes that can be analyzed, reducing sample…