Cytotoxicity

can lead to retarded growth and/or malfunction/formation of organs and also result in mortality by starvation and toxicity induced by silver nanoparticles. The increase in concentration of nanoparticles can also lead to nervous system disorder, cytotoxicity and necrosis which eventually lead to mortality and poor growth rate. So far no information exists about the toxic effects of silver nanoparticles on survival, growth and feed intake in fingerlings of freshwater catfishes. Since walking…

The initial concentration of RSF solution also plays an important role in the preparation of PTX-loaded RSF nanospheres (Table 2). When the RSF concentration increased to 15 mg/ml, the diameter of PTX-loaded RSF nanospheres changed corresponding to the lower concentration [RSF= 8 mg/ml]. It proves that the drug-loaded nanospheres range from 110~580 nm which apply to the intravenous chemotherapy is easy to be synthesized via varying the concentration of RSF solution and ethanol. Table 2…

1. Hypothesis Statements We are testing the efficiency of an in vivo tool for screening the effects of anti-cancer drugs on zebrafish embryos and comparing the results and their cytotoxicity with MTT assay of the MCF7 breast cancer cell line. The results will indicate if the drugs have similar effects on both breast cancer cells and zebrafish embryos. It is given that embryogenesis and carcinogenesis have similar molecular mechanisms, therefore it is expected that these cell types act somewhat…

Pharmacological activity of Sesbaniagrandiflora through invitro and invivo antioxidant mechanism 2. Antidiabetic activity of Sesbaniagrandiflora through hypoglycemic and hypolipidemic effect 3. Anticancer activity of Sesbaniagrandiflora through cytotoxicity in MTT assay on U-937 2. Source of information: the source of information through collection of vide literature survey of the medicinal plant and experimental research work. 3. Tools and techniques of research: Male Wistar albino rat was…

Concerning nanotechnological consumer products, the most rapidly growing is the use of nanoparticles (NPs).(47) So far the knowledge regarding the safety aspects of NPs is still in its initial phase and greater efforts is needed to understand the interaction of NPs with the human body. (48) Several studies have reported that NPs always showed more serious toxicity than bulks and suggested that their size and the dose were the key factors influencing NPs toxic effects.(49) Despite of this, large…

The TG and DTA curves obtained for the compounds (C1-C5) are shown in Figure 9. Table 4 lists the results of the thermal studies of these compounds with the initial and final temperatures (ºC), assignments of each decomposition stage based on mass calculation and DTA peaks. These assignments (Δm - Calcd.) are based on the structural fragments from the theoretical formulae of the compounds (C1–C5). This implies that the groups proposed in the right column of Table 4 are not necessarily the…

Chemical composition of wheat flour and lemon balm. Data represented in figer (1) indicate to the chemical composition of wheat flour and lemon balm as raw materials in the formula of g /1oo g of dry weight basis. The lemon balm contains (17.10g, 16.11g and 50.56g) of protein, fiber and carbohydrates respectively. While the wheat flour as raw material contains (11.86g, 0.69g, and 75.69g) of protein, fiber and carbohydrates respectively. Assay of polyphenolic compounds of lemon balm leaves. Figer…

Table: 9 FT- IR analysis of methanol extract of M. concanensis leaves S. No Peak values Intensity range Intensity Group assignment Functional groups 1 3972.43 0.0086 Unknown 2 3859.33 0.0412 Unknown 3 3805.79 0.0733 Unknown 4 3396.46 0.9280 Medium N-H stretch Amides, alcohols and amines 5 2987.43 0.2450 Medium C-H stretch Alkanes and acids 6 2946.27 0.2810 Medium C-H stretch Alkanes and acids 7 2912.38 0.2040 Medium C-H stretch Alkanes 8 2834.49 0.3170 Weak C-H stretch Aldehydes and…

The origin of T and B lymphocytes is through the lymphoid progenitors derived from the pluripotent stem cells within the bone marrow. Differentiation of cells that leave the bone marrow and proceed to the thymus include T lymphocytes (TL), as mature T lymphocytes will leave the thymus. Differentiation of cells that remain within the bone marrow include B lymphocytes (BL), as mature B lymphocytes leave the bone marrow and go to the secondary lymphoid organs. The production of BL begins in the…

Systemic lupus erythematosus (SLE) is an autoimmune disorder that affects over 250,000 people in the United States alone. 90% of the patients with SLE are female, which indicates that there is either an important role in female hormones or a protective role in male hormones. However, it is also possible that the gene is carried on the X chromosome, making males less likely to contract the disease (Rahman, et al. 929). Autoantibodies are generated in people with SLE, meaning that the humoral…