with Ebola. The virus attacks the host by attaching to host receptors using the glycoproteins studded in the envelope and is endocytosed into macrophagosomes. In order to fully penetrate the cytosol, the viral membrane must then fuse with the vesicle membrane, thereby releasing the nucleocapsid into the cytosol. As we already have discussed, the genomic negative sense ssRNA is utilized as a template for the synthesis of monocistronic mRNAs, and, using the host ribosomes and tRNA molecules, the…
In the summer of 2008 Canadian healthcare professionals noticed an irregularly high incidence of listeriosis cases (“Listeriosis outbreak timeline”, 2009), the disease associated with infection by Listeria. This concern was disregarded until people in a nursing home fell ill and sandwich meat from the same place tested positive for the presence of Listeria monocytogenes (“Listeriosis outbreak timeline”, 2009). On August 12, 2008, the Canadian Food Inspection Agency launched an investigation of…
1. Why is the cell theory significant (don’t just state the tenets, explain what it means and why it is a theory)? The cell theory is significant because of it’s three basic ideals or principles. The first is that all organisms are made from cells. This means that cells are the building blocks of life and technically, all of life is connected and related to each other by this tenet. In addition, by researching and examine one type of cell, the results can be assumed for all similar types of…
Cells have specific structures within them that allow them to carry out their functions; these structures are called organelles. Organelles have different functions within a cell that is called Division of Labor. They are also classified in two different groups, membranous and non-membranous. Membranous organelles are surrounded by a membrane while of course, non-membranous are not surrounded by a membrane. When describing the organelles and their function, first will be the membranous…
Anatomy of cerebral cortex: Brain is most complex organ in human body. The ability of brain for its functioning normally is manifestation of various activities it takes participation in various activities of day to day life, being it hidden from the view or perceptible, like walking, smelling, thinking, laughing, speaking, and hearing. These manifestations are results of very coordinated and complex electrical and chemical activity within and between the cells those makes up our brain. Abnormal…
Yeast Expression System for Glycoengineering Yeast expression system is an alternative to prokaryotic and higher eukaryotic expression system since it offers the attributes of speedy growth, ease to manipulate genes and low costing media like for microbes along with post translational modification and secretory expression like in higher eukaryotes. An increasing number of yeast strains are available for protein expression that are said to increase the yield of the protein, improves the…
Efflux is a method of facilitated transport carried out by protein complexes that fall into one of six currently identified classes based on their protein structure.44 These complexes are commonly able to recognize more than one substrate, making them a major cause of multidrug resistance, especially in Gram negative organisms.45 As many of these proteins are not expressed constitutively, it may be hard to predict the effect these complexes have on in-vivo treatment; many are tightly regulated…
Introduction: Investigating the effects of light intensity, NH4CL, and DCMU on the rate of electron transport in spinach thylakoid membranes was the purpose of this lab. Photosynthesis is the process that routinely drives electron transport across the thylakoid membrane but can be impacted when additional factors are added. Two phases known as the light reactions and the Calvin cycle makeup photosynthesis. Plastoquinone shuttle, water oxidation, and NADP+ reduction are the major factors of the…
JNK is one of the three branches of MAPK superfamily of serine/threonine protein kinases. Other members of this superfamily are p38 kinases and the ERKs (Kyriakis and Avruch, 2012). In mammals, there are 3 JNK genes: Jnk1, Jnk2, and Jnk3 on 3 different chromosomes, and each mammalian JNK gene has alternative splicing forms (Derijard et al., 1994). JNK is involved in many physiological and pathological processes. The JNK pathway plays a major role in apoptosis. JNK pathway is required for…
Why are respiration and photosynthesis cycle important. Photosynthesis and respiration cellular are the two main processes perform by most living organisms obtain energy from nature. They have an very important relationship went it comes to life survive. Photosynthesis help process plant cells to convert light energy from the sun into chemical energy while creating energy-rich carbohydrate molecules into glucose, while respiration cellular break down food molecules to obtain energy and store it…