Cystic fibrosis

The psychological impacts of living with cystic fibrosis Introduction A prevalent and life-threatening disease, cystic fibrosis (CF) can cause infections, lung damage, and respiratory failure via increasing the production of thickened secretions in the body’s organs (Abbott, Hart, Morton, Gee, & Conway, 2008). However, with the development of new treatments, the lifespan of individuals with CF have significantly improved. Unfortunately, these advancements have resulted in arduous treatments…

A total of seven people reside in the household. I am one of the five children in the home. I was diagnosed with a genetic life-threatening disease called, Cystic Fibrosis (CF) and many other problems such as bronchiectasis, atelectasis pulmonary, chronic sinusitis, pancreatic insufficiency, GERD, hiatal hernia, vitamin E deficiency, and many more. CF is a genetic disease that affects the exocrine glands. Consequently, this disease causes an imbalance at the cellular level between sodium and…

CYSTIC FIBROSIS. Many humans around the world are carriers of a genetic component that can cause their dependents to be born with a genetic disease that can affect their lives forever. Some of these conditions are currently under investigation by facilities which specialise in genetics testing. Cystic Fibrosis is one of many genetic disorders that can affect devilry the patient and their everyday life. Cystic Fibrosis are known to be a recessive disorder, meaning that both parents must a carrier…

When dealing with patients with Cystic Fibrosis it is important to know what education materials are needed for the patients and their families, whether it is in a hospital, a home, or in a specialized program. Some facilities in particular, will have educational materials online so that the patient’s families can print them out and review the material. The education materials will include instructions on how to perform the following: active cycles of breathing techniques, autogenic drainage,…

1) A.) The specific DNA changes caused by the delta F508 mutation, include a production of the abnormal cystic fibrosis protein. This mutation can only be inherited if both genes in pair of DNA carry the cystic fibrosis mutation. The specific mutation functions as a chloride channel, that has an abnormal amount of salt and water balance. Normally a chloride channel would help to maintain the right balance salt and water inside a cell, but those mutated with F508 mutation, are imbalanced causing…

The Effects of Cystic Fibrosis on Cell Signaling Cystic Fibrosis is a recessive genetic condition that causes the mutation of the CFTR gene, which contains instructions for making CFTR proteins. CFTR proteins regulate the transport of chloride in and out of cells; if the proteins don’t work properly, the cells are left with a high salt concentration and take up liquid from mucus in attempts to reach equilibrium.The disease most commonly affects the respiratory and digestive systems. In…

can affect lives greatly. One of the common known genetic disorder is ‘Cystic fibrosis’ which is a life-threatening disorder that affects the lungs, pancreas, liver, intestines, sinuses, and sex organs. In one of the article, ‘Gene Therapy for Cystic Fibrosis Shows Some Promise In Study’ by Christian George Acevedo published in the Science Times mentions that gene therapy can bring improve lives of people with Cystic Fibrosis. Gene therapy is a method in which a vector ‘virus’ carries genes…

Cystic Fibrosis What is Cystic Fibrosis? Cystic Fibrosis is a genetic disease that is one of the most common and lethal. The disease is usually noticeable in the victim by the age of 3 and impairs their ability to breathe and digest normally. This genetic disease is caused by a mutation of the CFTR gene (cystic fibrosis transmembrane conductance regulator). Everyone does have this gene, but only when it is mutated can it cause Cystic Fibrosis. Normally, the CFTR gene produces a protein whose job…

Name of disease and locus: Cystic Fibrosis is caused by a mutation in the cystic fibrosis transmembrane conductance regulator gene (CFTR; 602421). The gene is located on the long (q) arm of chromosome 7 at position 31.2. There are 5 different mutations of this gene that can cause cystic fibrosis. Frequency: 1 in 2500 newborn infants are born with cystic fibrosis. In 2013 just over 10,000 people were recorded to have cystic fibrosis in the UK. The most common mutation of the CFTR gene is…

To correct the mutation in the gene that lead to the development of cystic fibrosis, a team of Yale researchers led by Dr. Peter Glazer (Chairman, therapeutic radiology), Mark Saltzman (Chairman, biomedical engineering), and Dr. Marie Egan (professor of paediatrics and of cellular and molecular physiology), the collaborative team operated certainartificial molecules identical to DNA known as Peptide Nucleic Acids (PNAs), as well as donor DNA, to recover the genetic abnormality.Professor Egan…