Curcumin

Abstract: Curcuminoids including Curcumin ([1,7, bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione]) are being found in rhizome from the common spice, turmeric; or known as Curcuma longa L. Curcuminoids are phenolic compounds which carry the antioxidant and anti-inflammatory properties. Researchers have demonstrated these properties can develop medical and pharmacological treatments for diseases such as Alzheimer’s disease and cancer. Turmeric (Curcuma longa L.) is presented in this report as investing its chemical and physical properties as well as in medical and pharmacological applications to address the complex and benefits of this spice to the world. Keywords: Alzheimer’s Disease, Anti-inflammation, Anti-oxidant, Curcumin, Curcuminoids,…

Abstract: Curcumin is a spice that is the active ingredient in traditional foods, which has an incredible amount of beneficial properties, such as anti-inflammation and chemo preventive action. It can also act as an antioxidant and can even chelate irons. Currently, curcumin is involved in human clinical trials for many different conditions like multiple myeloma, Alzheimer’s disease, and colon cancer as a potential therapeutic agent. The purpose of this proposal is to present the current level…

Figure 1a. Size of nano curcumin. Image of curcumin nanoparticles taken with Transmission electron microscope (JOEL 2100F) showing particles having size distribution of 59.9 nm to 198 nm ( average size of 160 nm). Figure 1b. Bioavailability of nano curcumin. Mice were given I.P injections with curcumin/nanocurcumin (vehicle: PBS containing 10% ethanol) per mice at 100 mg/kg body weight and then bled at different time points via retro-orbital puncture and blood collected from each…

10. Indigestion and dyspepsia Curcumin has the ability to stimulate the gallbladder to produce bile. Bile is helpful in improving the digestive function. In another study, a placebo controlled study showed that turmeric was able to reduce gas and bloating in people suffering from indigestion. A scientific advisory board in Germany called German Commission E has approved the use of turmeric in curing various digestive problems. The commission is tasked with approving herbs for various treatments…

reduces the chance of a heart attack after a bypass surgery by half. Moreover, the polyphenol in turmeric called curcumin improves the vascular function as aerobic exercises. A study was carried out on 32 women in post menopause. They were divided in three groups: women who consumed curcumin, women who exercised and those who have not done any kind of treatment. The researchers assessed the elasticity, function and health of the vessels with an ultrasound. They assessed the lining or…

Opinions: A review from the National Institute of Mental Health and Neurosciences (NIMHANS) indicates that the bioavailability of polyphenols (curcumin, resveratrol, and tea polyphenols) in vivo needs to be improved before it can be considered an effective preventive or therapeutic treatment for dementia. However, once the bioavailability has improved via novel methods, they believe the clinical application of polyphenols against neurodegenerative diseases can be established. (M) Personally, I…

Particle size analysis The diameters of the curcumin, honey and curcumin+WPI+MH complex measured using Mastersizer were 3.480 µm, 1.349 µm and 20.911 µm respectively. The size of WPI measured with Zetasizer was 250 nm. Quantitative particle size and shape analysis provides information that has either a direct effect or correlation to issues such as bioavailability, solubility, formulation stability, and quality control. Scanning Electron Microscopy SEM micrographs of curcumin are shown in…

Benefits of Turmeric The benefits of eating turmeric are now well documented, to the point of declaring turmeric a superfood. But does turmeric deserve a place in your diet? Here are some of the health benefits of adding turmeric to your diet. Turmeric Helps Fight Aging Curcumin is one of the antioxidants found in turmeric. It is a powerful anti-aging supplement. Not only does curcumin fight the diseases that contribute to aging, but it also has anti-aging properties that protect the skin,…

When using Alamar Blue each color change means a specific effect the well had. In this case, red means the cells are alive, purple means the cells are dying, and lastly blue means the cells have dead. Figure 1 results, demonstrated that all the wells that have cells have the color change of red/pink meaning that the cells are all alive. Demonstrating that the reagent/chemical (Curcumin) didn’t have any effect to the cells (Hek293A). As seen for Row B: Columns 10-12 the color change was to…

13. Offer relief for rheumatoid arthritis Clinical studies have shown that curcumin is very effective in providing relief for rheumatoid arthritis as a result of its powerful antioxidant effects. Curcumin is highly potent because it can neutralize free radicals and other chemicals that are known to cause damage to healthy body cells and cell membranes. Common arthritis symptoms such as joint pain are caused by the presence of free radicals. Because of its high degree of efficiency, the effects…