Kidney Disease Mr Goodpasture has presented with the signs and symptoms associated with worsening of his chronic kidney disease (CKD) including signs of fluid overload and uraemia defined as the presence of excessive amounts of waste such as creatinine and urea in the blood (Mosby's Dictionary of medicine,nursing and health professionals, 2009). These include pitting oedema, basal crackles, agitation, increased temperature and premature ventricular complexes. There are also signs of…
Glucagon-like peptide-1 (GLP-1) is an incretin hormone involved in glucose regulation. Made in the intestines and released in response to the rise in glucose from eating, GLP-1 plays a critical role in glucose homeostasis by increasing insulin production and suppressing glucagon release. Additionally, GLP-1 slows gastric emptying and contributes to satiety. The combination of these factors contributes to glycemia, particularly following meals. Activity of GLP-1, much like insulin, is…
kits for serum total proteins, albumin, total lipid, triglyceride, total cholesterol, HDL-c, LDL-c, VLDL-c, alanine aminotransferase (ALT) and aspartate amino transferase (AST), alkaline phosphatase (ALP), blood urea nitrogen (BUN), uric acid and creatinine were purchased from ELIPSE, United diagnostic industry, UDI, Dammam, Saudi Arabia. Paraffin oil, carbon tetrachloride (SpectrosolW BHD chemicals ltd pool, England) and other chemicals and solvents were of highest grade commercially available.…
ineffective, clinician should add a 5-alpha reductase inhibitor in the treatment therapy. However, the authors disapproved the use of complementary and alternative treatments such as saw palmetto in management of BPH, as well as checking for serum creatinine measurement was not indicated since the incidence of baseline renal inadequacy in men with BPH is comparable to that in the general population (Pearson, & Williams,…
Offender seen today in chronic care followup of hypertension, chronic renal insufficiency, and hypothyroidism. Patient is currently in CIP. I reviewed her chart and noted that her renal function was normal in 12/2016. At the time, her blood pressure was good at 106/71. At her visit in 12/2016, it was felt that she was overly controlled and was having episodes of possible orthostatic hypotension with lightheadedness. She was on Norvasc, atenolol 50 mg once daily, hydrochlorothiazide, and…
& Sahay, R., 2014). The BUN/creatinine levels may also be abnormal, with a ratio of 20:1 or greater, if the patient is also experiencing dehydration (Sahay, M. & Sahay, R., 2014). I would first assess for her fluid volume status by looking for signs and symptoms of alterations in fluid…
full-term infants (Done, 2012). Caffeine is now one of the most commonly prescribed drugs in the NICU to treat apnea of prematurity. Later studies in preterm infants confirmed the diuretic effect of caffeine, and revealed a significant increase in creatinine clearance and urinary calcium excretion. The effect…
Nephrotoxicity is associate adverse effect of the anticancer drugs for solid and hematologic malignancies (Kintzel, 2001). Cisplatin, cisplatinum or cis-diamminedichloroplatinum (II) , a platinum-based drug, is one of the most frequently used anti-neoplastic agents. It has a potent anti-tumor action against wide range of malignancies, including testicular, ovarian, cervical, bladder and lung cancers as well as solid tumors resistant to other treatment regimens (Hanigan and Devarajan, 2003).…
Effective pain relief is a priority. Monitoring and documenting characteristics of pain and pain score including nonverbal cues, BP and HR changes are important. Nurses should make sure Mr. Peter’s systolic blood pressure (BP) is over 100 before administering glycerly trinitrate (GTN) sublingually, since it reduces oxygen demand and increases oxygen delivery (Berman, Kozier & Erb 2015). 6 rights (mediation, time, route, patient, dosage and documentation) need to be confirmed. The regime of GTN…
ecchymosis on his upper extremities due to multiple IV lines insertion and erythema on his sacral area due to limited ambulation. Due to pt.’s history of acute-on-chronic renal failure, his BUN level was 59, normal levels are 7 to 20 mg/dL; Normal creatinine levels for males is 0.6 to 1.2 mg/dL, his labs showed a value of 2.69. Also, due to pt.’s diagnosis of toxic encephalopathy secondary to possibly septic arthritis, P1’s WBC count was 13,000, normal levels are 4,500 to 10,000 mcL. All these…