Conserved sequence

In the 1960’s two scientists named François Jacob and Jacques Monod explored how the regulation of transcription of DNA affects the enzyme levels in a cell. They found this information through experiments in eubacteria and eukaryotes. According to Kireeva (2013) “However, the DNA-dependent RNA polymerase proved elusive until 1960, when it was independently identified in bacteria by Hurwitz and Stevens and in plants by the Bonner group” (p. 8325). There were also many experiments after these in…

representative of the prominent social class of males of the time period. As a window is made to permit the passage of light and air into any sort of home, it would seem like a ludicrous idea to keep this from happening. In fact, light and air is never conserved by any person, any acts of such would raise speculation by any sane person. This was not the case for the narrator, the window being a representative of inborn rights that this woman was wrongly being deprived of. In a brief look upon…

Biochemistry is the “structure and function” within living organisms through chemical processes (Revier). Being able to master the subject is a driven force that grasped my attention to continue pursuing my academics through this major. My interest for the subject grew as I conducted further research to determine the benefits of having a degree in biochemistry and how it would aid me in the long runs by having a successful future. Simultaneously, I enrolled in an Introduction to Biochemistry…

Objective: In-silico assessment analysis of Protein database entries of the Pf. lactate dehydrogenase (PfLDH) enzyme, considered as an important target for designing of anti-malarial drugs. Methods: PDB structures of the enzyme Pf. lactate dehydrogenase were downloaded from Protein Data Bank. These were subjected to ANOLEA energy assessment analysis and Swiss model was used to analyse Ramachandran plot. Results: The energy assessment analysis and analysis of Ramachandran plot were carried out…

We started off Wednesday, knowing we would be covering a topic that was completely new to pretty much everyone attending. We were covering transposable elements. These were first discovered by Barbara McClintock in corn kernels. She noticed that the corn kernels were either colored, or plain- but once in a while they were spotted. Most scientists at the time assumed that the chromosome for color had been repressed or had broken off. However, Dr. McClintock felt that if the chromosome had been…

Sirtuins and Histone deactylases (HDACs) Eukaryotic DNA is packed in a high level structure called chromatin, resulting from the assembly of an elementary unit, the nucleosome, and an octameric structure obtained from eight proteins called histones [1]. Histone deacetylation is a reversible process whereby histone and non-histone protein transfer the acetyl moiety from acetyl co-enzyme A (CoA) to lysines while histone acetylation is the direct opposite process whereby acetyl groups are removed…

For the Cross-National Work Experience assignment, I interviewed Lintao Shi on December 2nd, who is a non-American business person with working experience with Americans. He is currently working in Siemens JV Company as an accounting manager in the China division. He has an American boss and his colleagues are mainly from American and Germany. Because of the inconvenience of the location, I interviewed him through phone call for about 40 minutes. This is the first time I talked to Lintao Shi.…

Adenosine Triphosphate (ATP) is the body’s main source of chemical energy. It is produced by breaking down nutrients such as glucose, fatty acids and proteins, which are all found in food. At the start of the race, anaerobic pathways are used to provide a quick source of energy. Most of this energy is derived from the catabolism of fats. Since lipids are more reduced than carbohydrates, they are capable of storing more energy per unit weight. Triacylglycerols are the lipids used for energy…

Laboratory Findings Bacterial meningitis is the most common suppurative infection of the central nervous system (Mitropoulos, Hermsen, Rotschafer, 2012). It is rapid progressing and can lead to death or debilitating effects if not diagnosed and treated quickly. In order to diagnose a patient with bacterial meningitis a cerebral spinal fluid (CSF) examination is necessary. To obtain the CSF from a patient a lumbar puncture is usually done. When the physician is performing the lumbar puncture…

2013). Pax6 is a homeodomain transcription factor. This gene has been highly conserved, and as such, can be found in both vertebrate and invertebrate organisms (Klimova and Kozmik 2014). Pax6 is thought of as a master control gene for eye development because it regulates many other genes that lead to proper eye formation (Shaham et…