Hemophilia Hemophilia is a bleeding disorder in which blood doesn’t clot normally and results in excessive bleeding. The Jews were the first to recognize hemophilia and was described in the Talmud, which is a collection of Jewish writings, and stated that if two brothers had died after getting circumcised the next male baby from that family didn’t have to go through the procedure. Years later in 1803 a physician named Dr. John Conrad Otto in Philadelphia discovered that the disease was…
Introduction The predominant disease that mutant FGFR3 (fibroblast growth factor receptor 3) gene causes is Achondroplasia. Furthermore, Achondroplasia means the absence of chondrocyte formation in bones. Additionally, the transformation of chondrocytes into bone cells is prevalent in the limbs as well as the facial bones of humans (1). Therefore, the predominant symptom of Achondroplasia is bone growth retardation and is found in the limbs as well as facial bones. The majority of people…
Company (ASMC). The external environmental assessment was conducted with the PEST concepts. PEST is an acronym for political, economic, social, and technological. The terminology represents the framework organizations use to evaluate the external factors that affects their business performance. PEST can be used alone or in conjunction with other tools to help an organization's performance. The PEST concept as it relates to the Army Area Support Medical Company is based on the ASMC Mission,…
curtailed by the drug. MMPs are endopeptidases that degrade proteins of the ECM, and TIMP are their inhibitors. As expected, treatment enhanced the expression of pro-MMP-2 protein and repressed the expression of the TIMP-2 protein. Transforming growth factor-beta (TGF-beta) is a stimulator of collagen production and upregulates collagens in IPF. Nintedanib inhibited TGF-beta-induced secretion of collagens. Through these mechanisms, nintedanib promotes anti-fibrosis and slows the process of the…
The topic of intelligence can be described as one of the most controversial subjects in psychology, this is because a single definition of what intelligence is can never be agreed upon (Kleinman, 2012). Psychologists like Charles Spearman believe it to be a single ability whereas Howard Gardener believes intelligence is more than just one ability. Similarly, the concept of creativity is very hard to define as Amabile, 1996 (cited in Maley & Bolitho, 2015) states, ‘a clear and sufficiently…
(1999) argued that intelligence is not identical to what test measures and, therefore, ‘g’ factor is rather a subjective measure and…
et al., 2004). All five factors of personality are present to varying degrees within individuals, and it is principal that all five are studied in conjunction (Conard, 2006) however, agreeableness, conscientiousness and openness have shown greater correlations with Academic Performance than the remaining two factors (Poropat, 2009). A continuously replicated result in many studies concerning personality and…
a new inventory constructed to assess the pathological personality traits associated with DSM–5 PDs—the PID5—in relation to grandiose and vulnerable narcissism dimensions. An exploratory factor analysis (EFA) of a number of measures of narcissism and NPD was conducted to generate grandiose and vulnerable factors. “2 In this quote, it pretty much is saying that to diagnose someone based on the traits is difficult and that is when the personality trait comes into…
Willebrand disease is the most common bleeding disorder. It occurs when the body makes too little of the von Willebrand factor (VWF), a protein that helps blood clot, or when the VWF is misshapen and does not work the way it should. VWF is a carrier for another protein, called factor 8, that helps blood clot. When VWF levels are low or when VWF is not working properly, factor 8 levels are low as well and the body is less able to form stable blood clots. There are four major types of von…
In today’s world it seems like there is a growing number of people that are being plagued with mental health diseases. In particular Alzheimer’s appears to affect a growing number of people each year. Alzheimer’s is considered to be the “sixth leading cause of death in the United States today” (Latest Alzheimer 's Facts and Figures, 2016). While many research is being conducted to figure out the best way to combat this, there seems to be one deterrent that stands above all. This deterrent…