Collagen

7th November, 2014 Efficacy and safety comparisons between collagen derivatives and glucosamine sulfate supplements in treating adults with knee osteoarthritis. Linh Nguyen (11916828). Evidence based practice. University of Technology, Sydney I. CLINICAL SCENARIO During my clinical placement, I have come across a scenario where a 40 year old woman came into the pharmacy, saying that she had recently diagnosed with knee osteoarthritis (KOA) and was looking for a good dietary supplement as…

50-70°C. The activity is sustained without a marked decrease up to 80°C. Bromelain is quite effective at dividing proteins such as the collagen in steak. Bromelain first degrades 40% of the collagen in the sarcolemma followed by degradation of myosin in the myofibrillar component. Bromelain separates all the important peptide bonds that link the proteins in collagen and the muscle tissue begins losing firmness. However, bromelain efficiently softens the steak for chewing, but leaves it firm…

a greater exchange between soluble molecules. The papillary region consists of loose connective tissue which is characterized by a thin, poorly organized bundles of collagen fiber, which consist primarily of type I and type III collagen.12 Collagen fibers that are located in the papillary dermis contain a greater amount of collagen type III compared to the reticular dermis. Between the papillary and reticular dermis there is a mechanical separation (dermatoming) that defines a border between…

Osteogenesis Imperfec’ta Osteogenesis imperfecta (OI) is a genetic disorder that causes the bone to be fragile and break easily. It is also known as “brittle bone disease”. It is caused when there is a lack of collagen production. Collagen are what makes the bone strong, and the lack of collagen causes the bones to be weak and fragile, making it easier for it to break. OI affects 1 in 20,000 people. In the United States alone it is estimated to affect 20,000 at a minimum rate and 50,000 at the…

Cross-linking of collagen means the ability of collagen fibrils to form strong chemical bonds with adjacent fibrils (Ashwin and MaDonnell, 2010). In the cornea, collagen cross-linking occurs naturally with aging due to an oxidative deamination reaction which occurs within the end chains of the collagen fibrils and this natural cross-linkage of collagen explains why corneal ectasia often progresses most rapidly in adolescence or early adulthood but tends to be stable in patients after middle-age…

The main lesion in chronic schistosomiasis represents a complex delayed-type hypersensitivity response to sequestered living, dying or dead ova, that are trapped in tissues during the peri-intestinal migration or after embolization in the liver. Soluble egg antigen (SEA) and proteolytic enzymes released by ova provoke granulomatous cell-mediated immune response, with recruitment of eosinophils, granuloma formation and liver fibrosis (Cheever et al., 2000; Wynn et al., 2004). In schistosomiasis,…

Hypermobility is a spectrum disorder group that has similar conditions to joint hypermobility. Hypermobility is referred to as HSD. HSD are meant to be classified after the other possibilities are removed, such as any of the Ehlers-Danlos syndromes as well as hypermobile Ehler-Danlos syndromes. Hypermobile Ehler-Danlos is referred to as hypermobile EDS. Hypermobility syndrome is when your joints go beyond normal range. Usually joint hypermobility is influenced by inherited traits. Evidence of…

Task 2a - Explain the tertiary structure in detail ;consider protein shape, bonds involved, how these bonds are made (groups involved, location) give an example of protein having this structure. The primary and secondary structures are both present in a tertiary structure, the whole chain may then be folded further to give the protein molecule a complex globular shape that is known ate the tertiary structure. Similarly to the secondary structure the tertiary structure of protein is determined…

Introduction This investigation will compare and contrast four advanced skin treatments that are in industry today. The four treatments that will be compared and contrasted are:- - Injectable fillers - Chemical peels - Skin needling - Environ facials Throughout this investigation into the four treatments they will be explained in-depth the areas which each treatment covers, and what they do and also how and why the treatments are used. Also the advantages and the disadvantages of each…

that is used for facial rejuvenation. This minimally-invasive procedure is designed to stimulate collagen and elastin production, which helps to diminish the signs of aging. A More Youthful Appearance is Possible with Micro-Needling As we age, collagen production slows down: This decrease in collagen production causes wrinkles and/or sagging skin. Elastin is a protein that works in conjunction with collagen. Elastin can coil and recoil like a spring; thus, providing the skin with a more…