Collagen Collagen functions as a structural component. Collagen is the most abundant protein in the human body and is the substance that holds the whole body together. It is found in the bones, muscles, skin and tendons, where it forms a scaffold to provide strength and structure. Lupus is a collagen vascular disease that causes unique symptoms in each patient. Additional symptoms can include shortness of breath, chest pain, headaches, and dry eyes. People with lupus may have long periods of…
increases risk for diabetic foot ulcer. (Driver et al 891) Diabetic foot ulcer can eventually lead to amputation if not treated or if it is too advanced. now there’s a way to treat foot ulcers using synthetic skin grafts. using a bilayer of silicone and collagen, it temporally covers that open area. This allows the wound to heal without the interference of constant dressings and cleanings. Clinical were performed on patients on patient under the following inclusive criteria: “confirmed type I…
mild trauma or no cause at all. Multiple fractures are common with this disease since bones are weak. Although, in severe cases fracture of bones can occur before birth. This disease is caused by defective connective tissue and the lack of Type One Collagen. There are eight recognized forms of Osteogenesis Imperfecta ranging from Type I to Type VIII. Different signs and symptoms can differentiate the eight types of OI. My research is focused on OI Type I, which by the way is the mildest and…
Some of them will be discussed in this paper (gelatin, collagen, protein, tensile force, amino acid, triple helix, collagen fiber, and tensile strength). Gelatin is a protein food gotten by adding water to collagen, the most common animal protein. (Jiggle it: The history of gelatins, Aspics and Jellies) Gelatin is also a mild tasting protein derived from the collagen in animal tissue, and it is the only protein that…
The fibroblasts proliferate and synthesize and secrete proteins such as types of collagen during the phase of healing Hemostasis and degeneration. The function of these proteins is to reconstruct the extracellular matrix and provide a scaffolding- like framework for the developing endothelial and parenchymal cell. It is a t the point…
Advancement of medical imaging modalities, such as ultrasound, has significantly helped researchers and health professionals visualise dimensional and morphologic changes within the tendon, such as may occur with overuse injuries amongst athletes. Both Magnetic Resonance Imaging (MRI) and ultrasound have unique benefits and limitations. MRI may be better suited where there is a need for a differential diagnosis while ultrasound can be used to demonstrate active and passive movements in real…
At the beginning of the video, they are promoting a collagen powder to improve skin and to reverse aging. By definition, collagen is a strong elastic fibrous protein that holds together several body structures (Wardlaw p476). In the same video, Dr. Rosemarie Ingleton doesn’t necessarily advice the oral intake of collagen because it can be deposited to other areas of the body. Collagen does not only exist in skin because it is also an essential component of other connective tissues such as bones,…
truly cure the disorder is to destroy the mutated gene or gene product. However, there are some obstacles to such gene based therapy for osteogenesis imperfecta. Osteogenesis imperfecta in its most severe forms results from the presence of abnormal collagen molecule. This means that to cure it, the mutant allele must first be inactivated and then substituted in for its product. Researchers are still…
In its most recent season, Grey’s Anatomy presented an episode in which a married couple, joyfully expecting a child, discovers that their baby has a condition known as Osteogenesis Imperfecta (OI) type II. OI is a congenital condition also known as the brittle bone disease, and as the name says it all, it means that the bones of the body experience severe fractures. Due to the severity of the fractures, fetuses diagnosed with OI type II die within a matter of weeks due to cardiac and…
- There is a high degree of mineralization CaCo3 in the form of calcite - Contains fibers that bundle and form in a twisted plywood helical structure Horseshoe Crab The horseshoe crab has a composite of 3 layers: 1) Exterior shell - similar to crab but no mineral phase 2) Intermediate layer – vertical laminate 3) Inner core - open cell foam structure that is hollow in the middle Sheep crab The sheep crab shell is made of highly dense tubules that help enhance toughness. They also have a high…