Coagulation

Joanne’s body responds to hypovolemic shock by triggering the cardiovascular, renal, hematologic and neuroendocrine system for support. The Hematologic system responds to major blood loss by activating coagulation cascades and constricting the vessels that are currently bleeding by release of thromboxane A2 and platelets. What this does is form a colt on the bleeding site. Collagen is exposed by damaged vessels which cause fibrin production and stabilize the clots that have been formed. Usually…

treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and preventing complications associated with atrial fibrillation such as stroke2. For the past years, vitamin-k antagonist (warfarin) has been the primary treatment for a wide range of coagulation related indications3. However, limitations of warfarin have led to the discovery of a new generation of anticoagulants. Some limitations of warfarin use include a narrow therapeutic index, daily monitoring…

Complications of male circumcision over 10 years: A single center experience. Abstract: Introduction: Circumcision is the oldest and the most commonly performed surgical procedure all over the world for religious, ritual or medical purposes. It is a relatively safe procedure with a low overall complication rate. The aim of the study is to review the complications of male circumcision and how to avoid. Methods: Retrospectively we reviewed our institutional data base for all males operated in or…

initial dose is 10 to 22 ml/kg, depending on how much the veterinarian desires to increase the patient’s volume of red blood cells to the total volume of blood.3 Fresh whole blood is composed of red blood cells, white blood cells, platelets and all coagulation factors, albumin and immunoglobulins. When it is necessary for a patient to receive several blood components, or when they have lost more than 50% of their total blood volume, then whole blood is…

Acidosis Acidosis is defined as an arterial pH of less than 7.35, and can be a result of various disease states (Gerecht, 2014). Our blood pH in homeostasis is 7.35 to 7.45, so how in a trauma patient does it drop so low. Poor perfusion to tissue causes the body to work in a anaerobic state, this in return produces lactic acid. The lactic acid itself can cause a significant drop in pH level, but then think about the amount of crystalloid solutions we use for replenishment of blood volume.…

Homeostasis is a continuing balance of the body systems to maintain normal function. All systems within the body must work together to keep this balance. If one system should begin to function abnormally, it can throw off the body's entire homeostasis, or steady state. The cardiovascular systems distributes oxygen rich blood from the lungs to all of the body's organs and tissues by its heart pump and many arteries and veins. Cells throughout absorb what oxygen and nutrients are needed and then…

typically chronic in adults, but self-limited in children. The trouble with this there is not defining diagnostic that presents this disease clearly, instead the diagnosis is presented through the exclusion of other variables. Typically, patients have coagulation studies (COAG), liver function tests (LFT), and tests for infection. Other tests such as a complete blood count (CBC), a peripheral smear, bone marrow examination, coombs test, viral studies and an immunoglobulin quantitation are other…

PROTEOMICS AND NUTRIGENOMICS ASSIGNMENT: PUFA AS NUTRACEUTICAL SUBMITTED TO: DR. SANAULLAH IQBAL SUBMITTED BY: MAHAM ABID REGISTRATION NO. : 2014-ND-026 NUTRACEUTICAL Nutraceutical is referred to a functional food ingredient or a nutrient that possesses therapeutic properties and claim health benefits among people. CLASSIFICATION BASED ON CHEMICAL NATURE Nutraceuticals can be divided as follows: • Isoprenoid derivatives • Phenolic substances • Fatty acids and structural lipids •…

In recent decades, plenty of therapies are available for the ailments of cancer, despite of, this monoclonal antibody (MAb) is being advised by researchers for various aliments purpose owing to the versatile of usage. In the United States and Europe countries gains approval for MAb by FDA and European medicinal agency. Current, production of murine and humanized MAb will emerge the high specificity, affinity towards the epitope. Developed MAb holds the versatility features, like detection of…

Deca Durabolin Side Effects. How to prevent?Although Deca Durabolin side effects are rare, and androgenic problems are possible while taking 600+ mg a week. Common side reactions are blood pressure increase, blood coagulation decrease (it causes the often nosebleeds and bleeding nonhealing wounds), sebaceous glands hyperfunction and progressive acne. Some patients suffer from headaches and sexual super stimulation. There are possible the spermatogenesis delays, i.e. testicles start producing…