Clinical trial protocol

Introduction： Fixation and Decalcification are the common technique for technicians to preparations of patient or other samples. Both process are important for further diagnostics and clinical test. After processing fixation, the sample will become favor to support the high quality and consistent staining with H&E and for the long-term storage of paraffin blocks. Decalcification is specific for obtaining satisfactory paraffin sections of bone. The dense collagen of cortical bone become obviously…

Claim Most of the Animal Testing does not provide solution to the human treatment in biomedical research, and are not reliable to predict the human health. Along with this human benefit cannot justify the cruelty in animal testing during research. However, looking at the history of biomedical research, animal have been repeatedly use whether those testing were successful or not. It is true that human beings and animals are somewhat similar in biological and physical structure but does that mean…

Physicians objective is to find a legal team, preferably within the HCO that could examine the legislators of the AG’s decision. Furthermore, the LMH ethics committee prefers to find an on-staff volunteer lawyer with clinical experience. Ultimately, all ethics committee members unanimously convey that they want to change to happen. The question remains how community involvement in addressing the issue shall be the most effective. The topic of DNR is necessary for the elderly with chronic illness…

1. Introduction Posaconazole (POS) 4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furanyl]methoxy]phenyl]-1-piperazinyl]phenyl]-2-[(1S,2S)-1-ethyl-2- hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one (Fig.1)[1].Available under the brand names Noxafil oral suspension(40mg per mL) and Noxafil 100mg Gastro-resistant tablets [2] from the MSD (Merck Sharp & Dohme Ltd, Hertford Road, Hoddesdon Hertfordshire EN11 9BU United Kingdom)- Used for the Prevention of…

There are many types of consumers within society that utilize products on a daily basis. These people rely on products to beauty one’s self or use products to protect one’s skin to the effects of age and sun damage. A licensed esthetician is a professional who utilizes skilled techniques with the use of cosmetic products for each client. The following sections will describe the importance of understanding the differences between consumer use products and professional use products in…

1. In a monopolized market the monopolist is the one to set the price. When I think of a monopolist I think of John D. Rockefeller and his quest to try and control the oil market. He could have eventually controlled the whole market and set any price he desired. There is a modern day pharmaceutical problem arising that I recently read about and I feel it is becoming monopolistic. The Turing Pharmaceutical AG who recently acquired a drug called Daraprim to help those with AIDS, shot the price up…

Evidence Based Medicine Introduction Evidence based medicine has long been held in high esteem by physicians and for good reason. It provides the best possible roadmap for improving quality care for patients. In addition, certain clinical practice guidelines (CPG) have been established as part of the specific paradigm involving electronic medical record (EMR) keeping. This has all been designed to improve patient well-being, give physicians an opportunity to make informed decisions, and improve…

The process of developing new drugs typically involves clinical trials. When a new medication, vaccine, or similar product has been developed, researchers must ensure that they are effective and safe for people to use. To experimentally test that a drug produces the intended effect, most clinical trials use a randomized controlled trial (RCT) design. In this type of experiment, some people are assigned by chance to the active intervention and others are assigned by chance to a controlled…

Data extraction: The title and abstract of studies with potential relevance for the review were obtained and screened independently. Studies without abstract, but with a title suggesting relevance to the subject of the review, were selected for full text screening. The selected articles were independently read in detail to verify whether they passed the inclusion/exclusion criteria. The references of the articles were screened for any relevant data for the review. The extracted data included:…

Summary: The writers of this article conducted an experiment that experiment with new therapies that target pathway of PAH to treat ES, which has been shown to be more effective in comparison to other treatments. Multiple therapies such as, phosphodiesterase type 5 inhibitor, endothelin receptor antagonist Bosentan, and prostacyclin analogs are tested and compared to one another in this piece. The experiments have led to the conclusion that the combination of these therapies offer one of the…