Clinical trial protocol

INTRODUCTION: Pharmaceutical field is the research and development intensive field. The search for safe and effective drugs continues to be major efforts for all the pharmaceutical industries. There are enormous complexities for discovering and testing new drugs because of the many aspects of safety, efficacy and economics which determines the acceptability of a drug. Nose is one of the delicate organs of the human body, as a result of which nasal drug delivery is challenge for formulator.…

Drug dissolution testing is important so that we can be able to understand the trend followed by the drug in the biological system. USP Apparatuses are used for dissolution testing but the shortcoming of some of these apparatuses is not being able to mimic the conditions in the biological system. USP Apparatus 3 have recently been developed and has shown to have superiority over the other USP Apparatuses 1 and 2 based on the mentioned disadvantage, and others. USP Apparatus 1 is called the…

This was the first study to investigate the pharmacoeconomic impact of voriconazole versus posaconazole as antifungal prophylaxis in patients with AML. It showed that posaconazole is more cost-beneficial prophylactic agent than voriconazole. The cost per patient associated with initial prophylaxis was higher for voriconazole as compared with posaconazole. This difference in cost was mainly due to the fact that while posaconazole was only received as an oral formulation, three patients on…

researches of breast cancer have been indicated that, CEA and CA15-3, are the two most broadly used tumor markers in the clinical fields for more than 30 years20. In recent years, many studies have shown that, circulating tumor markers, are important diagnostic instrument, in under surveillance of breast cancer patients8, also it can be used, for surveillance goals in clinical studies…

deep vein thrombosis and pulmonary embolism, has been increased in cancer patients, adversely affecting their prognosis. Low-molecular-weight heparins are recommended as efficacious and safe anticoagulation treatment in cancer patients. However, in clinical practice, oncologists prefer oral anticoagulation, especially if long-term or extended treatment is necessary. The novel oral anticoagulants have recently emerged as an alternative to the standard therapy owing to the ease of administration,…

The Effectiveness of “Winter Stars” By Larry Levis The poem “Winter Stars” by Larry Levis starts out depicting a story that a boy is remembering from his child hood. Levis vividly depicts the boy’s father “breaking a man’s hand” (Levis) on a piece of farming equipment because the man named “Rubén Vásquez” (Levis) attempted to kill him with a well described knife. His father then proceeds, with no empathy, to grab some lunch and listen to some music. The boy then contemplated the meaning of life…

The topic that I selected is increasing the evidence based practice use. Evidence based practice (EBP) is one of the popular topics in nursing today. It is defined as a “problem-solving approach to clinical decision making within a healthcare organization that integrates the best available scientific evidence with the best available experiential evidence” (Hain & Kear, 2015, p. 2). Applying evidence based practice into our daily nursing practice can improve the quality of care of the patients…

the on-campus clinic experience at the technologically advanced Robbins Center and the multitude of off-campus clinical practices that are accessible to students in Boston and surrounding areas, I feel confident that I will gain experience in all areas of the broad scope of practice of an SLP. I believe my experiences as an undergraduate make me capable of excelling in the classroom, clinical field, and research field of Emerson’s program and beyond. My goal is to strengthen and add to these…

Results: Figure 1; Repellent activity in percentage of the volatile extract of C. sinensis, C. limon, C. aurantifolia and positive control on Camponotus nearcticus. The activity was generally high on C. nearcticus with positive control recording 100% activity, C. limon having 95% and C. sinensis having the lowest activity of 82.5% activity. Figure 2; Observed percentage lethal activity of the volatile extracts on C. nearcticus at five concentration points after 180 minutes of exposure…

The futuristic, seemingly inconceivable concept of a medication that could replicate exercise is examined by Nicola Twilley in “A Pill To Make Exercise Obsolete”, published in The New Yorker. Investigating several such exercise-supplements that exist today, Twilley explores the idea of exercise and its health implications on a broad scale; Assessing how exercise was viewed throughout human history, how it exists in the natural world, and how it seemingly benefits innumerable systems in the human…