Genetics To Down Syndrome Genetics describes the makeup of our cells, genes, chromosomes, and phenotypes. When there is alter in a gene or a duplication of a chromosome, it can lead to a certain diseases. One of the main diseases known today from a duplication of a chromosome is Down syndrome. John Down first put a name to Down syndrome in 1866, but artifacts from Mexico and Saxon documented some cases of Down syndrome in individuals, and also some were found in paintings of the Renaissance in…
they produce large quantities of progeny. Besides these reasons, this species has more advantages for genetic analyses. While most organisms have a higher chromosome count, D. melanogaster has only four chromosome pairs, three pairs of autosomal chromosomes and one pair of sex chromosomes, making it fairly easy to determine on what chromosome…
distinct phases which prepare the cell for separation as well as an additional phase where the cell can exit the cell cycle. The G1 phase is the first phase in which the cell commits to divide and grows in preparation. The S phase replicates each chromosome to create pairs of sister chromatids. The G2 phase synthesizes proteins in preparation of cell division in the M phase. The last phase of the cycle consists of 4 sub phases which the sister chromatids are separated and enclosed in a nuclear…
Previous studies have established that the gene responsible for Huntington’s disease (HD) is located in chromosome 4 – labeled as 4p16.3. Early symptoms of the disease include chorea or involuntary movements, loss of balance, as well as cerebral atrophy1. Although the disease has a late onset, juvenile form of the disease is also probable. The disease is manifested in children and teenagers and is characterized by transmission from an affected father (paternal transmission effect), unusually…
states that during the formation of gamete the two allele pairs separate randomly. The second law is independent assortment which states during gamete formation each pair of the allele will segregate independently of the rest of the pairs of the chromosomes. The third law is the law of dominance which is that alleles can be dominant or recessive with the expression of the dominant trait when a minimum of one dominant allele is present. Mendel described inheritance as the passing of genetic…
The neurological components of Hutchinson-Gilford Progeria Syndrome Hutchinson-Gilford Progeria Syndrome (HGPS) is a genetic condition affecting 1 in 4 million live births. HGPS is often described as a segmental premature aging syndrome meaning that not all features of aging are observed. For example, individual with HGPS do not experience declines in neurocognitive function (Shah, 2017). Children with HGPS appear typical at birth, but noticeable delays in growth begin to appear between the…
1940 by alexander wiener and Karl Landsteiner . Rh blood group is the most complex genetic of all blood type system, because it hooks 45 different surface antigen on the surface of the red cells that are controlled by two closely linked genes on chromosome 1. The antiserum for blood sample was the outcome results of the research that was done on the rhesus monkeys which lead to the naming of the Rh system. (Oneil, 31-07-2015) The RH factor works in a certain way, when the antiserum agglutinate …
to get us ready to try to reproduce. Our bodies are made up of DNA. DNA is made up of chromosomes. We get 23 chromosomes from our dad and 23 chromosomes from our mom. We are made up of 46 chromosomes to make us whole. Chromosomes come in pairs, as partners. The only time they get together is during Meiosis. This is the process in which the genes between the two chromosomes in each pair producing chromosomes with new genetic combinations every time. Each…
If you go to the circus today, you'll see elephants, clowns and cotton candy - not much of a freak show. Circus acts focusing on physical abnormalities might be a thing of the past, but that doesn't make them any less interesting. Below we present the 10 most bizarre circus performers who used their abnormalities to their advantage.Myrtle Corbin was born a dipygus, which means her pelvis and legs were duplicated.Prince Randian, also known as the snake man, was born without limbs.Here we have…
the loops contained tiny parts where a protein is called CTCF.Researcher found large parts of gene looped together. There were a lot of experiments that took place in my article talking about looping and folding DNA.They also talk about Y chromosome and X chromosome with the 3-D experiment. Folding happen in cancer cells they can use 3-D maps to help find a cure. This is just some of the experiments they did in the article I…