Chromosomal translocation

Chimerism started with a Greek mythology of Oedipus which is an unfortunate fellow he saw his father that marrying her mother. But she committed suicide and Oedipus saves many people in the city of Thebes because of a terrible monster. The story is about a monster feared by everyone because it has inherent power that can defeat anyone and it also has intelligence as a person. This intelligence can be deadly combination of chimera or also called chimerism a creature in Greek mythology may have…

for the disease (1). Trisomy 13, another name given to the disorder, is when a person has "3 copies of genetic material from chromosome 13, instead of the usual 2" (5). When the extra chromosome is attached to another chromosome it is known as translocation, which is a cause of this…

Preimplantation genetic testing is a genetic technique in which cells are removed from embryos to examine chromosomal abnormalities in vitro fertilization before a woman gives birth (King). Embryos made through in vitro fertilization would face genetic modification to avoid passing the defects onto future generations. After modification, only embryos free of abnormalities would be placed into the mother’s womb. This technique is targeted for parents who have a high risk of passing a fatal…

abnormality as the primary cause of oncogene formation. This bone marrow stem cell disorder is associated with a chromosomal translocation, which leads to the formation of an oncogenic protein. This translocation and oncogenic protein is then responsible for inhibiting DNA repair and the enhancing the susceptibility of further genetic abnormalities. CML has three phases as the chromosomal abnormality accelerates the unregulated growth of myeloid cells in the blood and bone marrow. This abnormal…

group. The telomeres are indicated by the circles at ends of linkage groups. Breakpoints of chromosomal rearrangements distinguishing the taxa are indicated by the double squiggles. The existence of homologous gene between the populations shows that Poaceace is relatively conservative. However, certain lineages in this family appear to be rapidly evolving. The genome of wheat and rye are different by 13 chromosomal rearrangements after only 6 million years of divergence (Devos). This rate is…

FOXO proteins are the O class of the Forkhead family of proteins. Forkhead protein (FOX) was first discovered in Drosophila and when mutated results in a head structure that resembles a fork (Wiegel et al 1989). Over 100 FOX proteins have been identified since and classified as FOXA to FOXR depending on sequence similarities. The FOX family of proteins function as transcription factors and their defining feature is a DNA binding domain known as the fork head domain (Lai et al 1993). This domain…

DOWN SYNDROME: A LIFE-LONG DISORDER Imagine facing two choices: parents having to abort their unborn baby, or they go through the pregnancy knowing their child is going to have Down syndrome, knowing that raising him or her will not be easy. Many parents face this choice everyday. According to Peggy Parks, author of Down Syndrome, 80 to 90 percent of unborn babies diagnosed with Down syndrome are aborted (19). Everyday, all around the world babies are diagnosed with Down syndrome and parents…

Turner syndrome, also known as TS and gonadal dysgenesis, is a chromosomal deficiency affecting over two million women that occur when two of the X chromosomes in a female’s DNA are either incomplete or missing entirely. It usually becomes apparent when a female is only a few years old, or even shortly following her birth. The missing genetic material of the X chromosome keeps the female body from maturing on its own. Because Turner syndrome is different for every female and an individual…

methylenetetrahydrofolate dehydrogenase which is accountable for pigment defect. The mutation results in repetitive DNA segment that involves ~140 iterations of the sequence AGAGAGA. Transcription and translocation are required in which these repeats are partially responsible for the phenotype (Rong et al. 1998). Another chromosomal effect vermilion has that disturbs its phenotype…

and Down Syndrome are becoming more and more common. This research paper will discuss what these diseases are, how rare they are, and what characteristics are common with these diseases. Down Syndrome Down syndrome is a chromosomal condition that can’t be cured. It occurs when a child is born with a partial or full copy of chromosome 21. This extra genetic material changes learning and development courses. Some ways to identify if a child has it are: a single,…