Chromosomal translocation

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    Down syndrome (or Down’s syndrome) is a generic chromosomal disorder which is caused by the presence of an extra chromosome 21. It is also known as “trisomy 21”. This condition leads to deficiencies in both cognitive ability and physical growth. It is typically related with physical growth delays, characteristic facial features, and minor to moderate intellectual disability. The IQ level of an adult decreases because of this. This genetic disorder, which differs in severity, sometimes causes…

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    lymphoid precursor cells, also known as lymphoblasts. During the early development of these cells, they experience an interruption of their cell development. This is usually due to an abnormal gene expression, mostly caused by chromosomal translocation. Chromosomal translocation happens because of a chromosome abnormality that occurs in the rearrangement of the nonhomoglous chromosomes. The lymphoblasts then replace the normal elements in the bone marrow causing a decrease in production of…

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    Down Syndrome

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    infectious diseases, heart abnormalities, and fluctuating levels of mental retardation, in most cases severe. Information on Down syndrome, including signs, symptoms, and diagnosis; genetic information such as a detailed description on trisomy 21, and translocation; an expanded and comprehensive history on Down syndrome; modern-day individuals…

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    Non-Hodgkin’s Lymphoma (NHL) is a type of cancer that originates in the lymphatic system, the system in the body that is responsible for fighting disease, and is known to be the 6th most common cause of cancer death.1 There are many different types of lymphoma and is classified based on multiple factors such as the pathophysiology of the disease, how the disease metastasizes to other organs and its response to treatment. The two main types of lymphoma are NHL and Hodgkin’s Lymphoma. Hodgkin’s…

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    C-Myc Synthesis

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    C-myc is a transcription factor that is involved in the strict regulation of the cell cycle. It regulates genes that promote the induction of the cell cycle and it is also involved in apoptosis. The c-myc ¬gene is one of the most commonly activated oncogenes and has been found to be overexpressed in many cancers. Activation of this oncogene may contribute to as many as 100,000 cancer deaths per year in the United States alone (Dang et al., 2006). The discovery that this gene is involved in so…

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    What Is Trisomy 21?

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    Genetic Disease Project: Trisomy 21 What is Trisomy 21? For starters, Trisomy 21 is another for a genetic disease called Down Syndrome. Genetic Home Reference says “Trisomy 21 is a chromosomal condition that is associated with intellectual disability, a characteristic facial appearance, and weak muscle tone (hypotonia) in infancy. All individuals affected experience cognitive delays, but the intellectual disability is usually mild to moderate. You get Down Syndrome by having a extra set of…

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    Chimerism started with a Greek mythology of Oedipus which is an unfortunate fellow he saw his father that marrying her mother. But she committed suicide and Oedipus saves many people in the city of Thebes because of a terrible monster. The story is about a monster feared by everyone because it has inherent power that can defeat anyone and it also has intelligence as a person. This intelligence can be deadly combination of chimera or also called chimerism a creature in Greek mythology may have…

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    Down Syndrome Research Paper

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    DOWN SYNDROME: A LIFE-LONG DISORDER Imagine facing two choices: parents having to abort their unborn baby, or they go through the pregnancy knowing their child is going to have Down syndrome, knowing that raising him or her will not be easy. Many parents face this choice everyday. According to Peggy Parks, author of Down Syndrome, 80 to 90 percent of unborn babies diagnosed with Down syndrome are aborted (19). Everyday, all around the world babies are diagnosed with Down syndrome and parents…

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    for the disease (1). Trisomy 13, another name given to the disorder, is when a person has "3 copies of genetic material from chromosome 13, instead of the usual 2" (5). When the extra chromosome is attached to another chromosome it is known as translocation, which is a cause of this…

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    group. The telomeres are indicated by the circles at ends of linkage groups. Breakpoints of chromosomal rearrangements distinguishing the taxa are indicated by the double squiggles. The existence of homologous gene between the populations shows that Poaceace is relatively conservative. However, certain lineages in this family appear to be rapidly evolving. The genome of wheat and rye are different by 13 chromosomal rearrangements after only 6 million years of divergence (Devos). This rate is…

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