Chromosomal translocation

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  • Essay On Chromosome Looping

    DNA organization within cells is a complex and sophisticated process. This high level of complexity is due to the hundreds of thousands of interactions that can be enabled through organization. It is a known that promoter elements and enhancer elements work in unison to regulate gene expression. Often times enhancers are found hundreds of kilo-bases away from their interacting promoter elements. These enhancers initiate promoter activation via interactions amongst transcription factor binding…

    Words: 1576 - Pages: 7
  • How Does Down Syndrome Affect Family

    Syndrome”). Another way that Down Syndrome can occur is by Translocation. This is less common than Trisomy 21 and accounts for only three to four percent of all cases of Down Syndrome. Translocation happens when a piece of the 21st chromosome breaks off and the the child receives an extra portion of chromosome 21. This is different than Trisomy 21 because it may show that one of the parents of the child with Down Syndrome has chromosomal material that is in an abnormal manner. Counseling…

    Words: 1829 - Pages: 8
  • Polyploidy Essay

    and structure through genetic and epigenetic changes. Epigenetic changes are mediated by RNA and chromatic remodeling and occur vie regulatory pathways. Genetic changes occur through deletion, mutations, loss of DNA sequence, transposition, and translocation. There are several significant effects of polyploidy in plants, such as: dipliodization, speciation, conservation of species, difference in gene composition, variations in gene expression, neofunctionalization and subfunctionalization, and…

    Words: 707 - Pages: 3
  • Downs Syndrome

    take place in early development when there are some cells who lose an extra chromosome 21 which was present at conception. Symptoms for this form vary between the Trisomy 21 but this depends on the amount of cells which have an extra chromosome. Translocation Down’s syndrome This type of Down’s syndrome is caused when there is a chromosome which breaks off and attaches itself to another chromosome. There are three 21 chromosome but one 21 chromosome attaches to alternative chromosome. Health…

    Words: 1955 - Pages: 8
  • Down Syndrome: A Genetic Disease

    genetic chromosomal disorder and cause of learning disabilities in children.” ("Down Syndrome - Mayo Clinic") History: Down Syndrome was discovered in 1866 by a British physician named John Langdon Down, which is where the name Down Syndrome came from. This genetic disorder was first referred to as Mongolism. The name Down Syndrome did not start being used until the early 1970s. In 1959, a French Pediatrician/Geneticist…

    Words: 1281 - Pages: 6
  • Acute Myeloid Leukemia (AML)

    Acute Myeloid Leukemia is categorized by a growth in the number of myeloid cells in the marrow and puts a block in their maturation in the earliest stage of development. In many cases, it includes the encouragement of irregular genes through chromosomal translocations. (1). The diagnosis of AML involves the presence of at least 20% leukemic…

    Words: 1302 - Pages: 6
  • Causes Of Down Syndrome

    Down Syndrome affects physical growth, facial characteristics, and intellect. Also known as Trisomy 21, it is a genetic mutation in which a person is born with an extra chromosome. These chromosomes are rod-like structures where genetic materials are stored and grouped. The nucleus of each cell in the human body contains 23 chromosomes, half, being inherited from each parent. The added chromosome changes the systematic development, affecting not only physical traits but mental as well. Common…

    Words: 1530 - Pages: 7
  • The Cause Of Cancer

    A body is made up of cells, and in each cell, genes are found. Genes are passed down to children from parents, and over time genes can mutate. Mutations, or changes, in genes acquired from a mother or father, or genes damaged throughout a person’s life, is what contributes to the growth and development of cancer. Normally, one mutation will not cause cancer because the human body can correct that change, but with a multitude of mutations over time cancer becomes more probable. There have also…

    Words: 1239 - Pages: 5
  • Irx3

    Figure 1: Shows the gene expression changes found in Arabidopsis after the insertion of the IRX1, IRX3, and IRX5 mutants(Brown). 1A shows the principal component data collected from the targeted areas of the plant(Brown). 1B shows a comparison of gene expression of the base and tip of the stem and the change of level(Brown). 1C shows the slope of genes most likely to be related to IRX3(Brown). From Figure 1B, it is shown through analysis that there are several hundred genes that show an increase…

    Words: 1984 - Pages: 8
  • Lung Cancer Essay

    Lung Cancer Lung cancer is a malignant neoplasm of the lung tissue characterized by an uncontrolled cell proliferation. It is also referred to as carcinoma of the lung. This neoplasm arises from epithelia of the lungs, bronchi and trachea. Lung cancers can be of epithelial cell origin (carcinoma) or mesothelial cell origin (malignant mesothelioma). Lung cancer begins with inactivation of tumor suppressor genes or with activation of oncogenes. Carcinogens bring about mutation in the genes that…

    Words: 1525 - Pages: 7
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