Chemotherapy regimens

Vinorelbine also known as Navelbine® is an anti-cancer chemotherapy drug. It belongs to a class of chemotherapy drugs called vinca-alkaloids; which can be categorised as spindle poisons1. Vinorelbine and Vindesine are semi-synthetic derivatives from the first generation of vinca-alkaloids; Vinblastine and Vincristine2. These original vinca-alkaloids were derived from dried leaves of the Madagascan periwinkle (vinca rosea) plant1. Madagascar periwinkle is also used in the treatment for diabetes,…

In the article “Circadian Clock, Cancer, and Chemotherapy,” the authors discuss the relationship between the circadian clock, cell cycle, DNA repair, and apoptosis. The authors then relate these relationships to cancer and treatment of cancer. The article backs their claims with numerous studies performed on both animal and human subjects. It also describes the importance of circadian rhythm in timing of drug delivery for cancer patients. This treatment method has been given the name…

always associated with such type of side effects, and this one of the major problems associated with chemotherapy. Chemo protective agents are still a new ground of study and study will likely give up agents with superior selectivity for healthy tissue as well as the aptitude to protect a larger number of tissue types. A variety of drugs have been developed to organize side effects related to chemotherapy, including Erythropoietics for anemia (Epogen, Darbepoetin), Antiemetics for nausea and…

Docetaxel, also known as toxetere, is used as an anti- cancer chemotherapy drug. It is used to treat cases of breast, lung, prostate, head, and neck cancer. Docetaxel is administered through IV. The amount of docetaxel patients receive depends on a lot of factors. Factors such as height, weight, the type of cancer being treated, and how far along the cancer has developed factors into how much medicine the patients receive. Use of docetaxel can result in low white and red blood cell counts. This…

strength and form: Unituxin 3.5 mg/mL concentrate for solution for infusion. • Route of administration: intravenous infusion • Dinutuximab is indicated to treat high-risk neuroblastoma in people aged 12months-17 years, who have received induction chemotherapy previously and achieved a minimum of a partial response, followed by myeloblative therapy and autologous stem cell transplantation. • Mechanism of action drug substance: dinutuximab is a monoclonal chimeric antibody. Dinutuximab reacts…

Regimens used in the ductal subtype can be used in the same way (21). Some studies showed an advantage in using anthracycline based chemotherapy in NEBC (22), whereas others didn’t show this benefit (2) (14). Some reports recommended the use of anthracycline based chemotherapy according to Ki-67 expression, usually if ki-67 is around 10%. For poorly differentiated carcinomas, especially…

Society as we know it today has become dependent on the use of synthetic materials, natural materials that have gone through a chemical change to become man-made, therefore, synthetic. Some synthetic materials are easier to create than others, these materials range from plastic, to nylon, to cocaine, to medicine, and much more. Synthetic materials play a large role in our lives and they surround us everyday, although, it hasn't always been this way. Earth and humans aren't always accustomed to…

Many people are discovering the ways in which medical cannabis can help them. Whether it’s managing the side effects of chemotherapy, keeping a chronic pain disorder under control, or coping with a mental health condition, cannabis has many medical uses. Many people who are authorized cannabis have pre-existing conditions, such as cancer, PTSD, or chronic pain. While cannabis can help you manage a condition, it’s most often used in conjunction with other therapies and medications. This…

platinum-based drugs such as Picoplatin and Satraplatin might further broaden their applicability to tumour types such as prostate cancer and small-cell lung cancer, respectively. There will probably be continued and extended use of platin-containing regimens with the new generation of molecularly targeted therapies, as exemplified by the recent approval of bevacizumab in combination with carboplatin and paclitaxel in patients with lung cancer; breast cancer provides additional possibilities. …

significantly by the increasing complexity of cancer care the patients are receiving as well. Due to increasing demand, oncology clinics are experiencing increased workloads resulting in delays in laboratory results, oncology appointments, and chemotherapy administration; thus, affecting wait times, patient satisfaction, and clinical efficiency. The focus of this paper will be on visit de-coupling in an outpatient…