tetrahydrocarbazoles having the significant biological properties. The newly substituted tetrahydrocarbazole derivatives were prepared from substituted phenylhydrazine and cyclohexanone in glacial acetic acid under reflux. These intermediates on reaction with substituted aromatic acid chlorides in alkaline media finally converted to N-Substituted tetrahydrocarbazoles. Fifteen compounds are synthesized and charaterized by their melting point (MP), IR, NMR, MS and elemental analysis. All the…
Chemical reactions can be categorized based on the release or absorption of energy. For instance, chemical reactions that release energy are known as exothermic reactions and have a positive change in enthalpy. Moreover, chemical reactions that absorb energy are endothermic, which have a negative change in enthalpy. Since the energy released is usually heat, keeping track of the heat flow in reactions will help determine the change in enthalpy of a reaction. Observing the measurement of heat…
CHAPTER 4 RESULT AND DISCUSSION 4.1 Preparation of Bis-Thiourea Derivatives The mixture of heptanoyl chloride and ammonium thiocynate with 1,4-phenylene diamine appeared as homogeneous solution. White precipitate was formed immediately when the solution was filtered into the beaker containing ice cubes. Then, the precipitate was filtered again and rinsed by ethanol before being dried in the desiccator. The physical data of the synthesized bis-thiourea derivatives are shown in Table 4.1.…
Introduction: Enzymes play a major role in biological systems to catalyze and control different reactions. The study of enzymes’ behaviors toward substrates and products is significant to understand various enzyme catalyzed reactions in living organisms. One of the most important enzymatic group is cytochrome P450 (CYP450) which contribute to the metabolism of many endogenous as well as exogenous substances such as drugs. Although there are several subtypes of CYP450 family, CYP450 1A1 is going…
change happen. Chemical change is the process of bonds breaking and forming new ones. All the atoms have to stay in the compound in a chemical change, but you…
with solid iron metal. The techniques used in this lab were weighing by difference, quantitative transfer, and vacuum filtration. At the end of the experiment it was found that iron was the limiting reactant and iron(II)sulfate was a product of the reaction between 7.0002g of copper(II)sulfate and 2.0101g iron metal which produced 2.3037g of copper product with a percent yield of 100.72%. Introduction: Much research has gone into studying how to best utilize the degradation abilities of…
words “poly” which means many and “mer” which means parts. Polymers are substances which have large number of repeating structural units repeated in the same type of linkage. The chemistry that deals about polymers is called polymer chemistry and the reaction is called as polymerization. Polymer chemistry have a wide range of application in day to day life and the research and recent advanced in this field are both industrially and academically notable and increasing day by day . In this review…
of an electric current. Electrochemical machining is in general differing to electroplating where the metallic ions wandering through the electrolyte solution set down on the surface of the cathodically connected work piece. The electrochemical reactions taking place in the electrochemical machining process are as…
titration. A chemical reaction occurs when two or more substances change to form different molecules. In each reaction there are ratios between each reactants. Certain amounts of each reactant are needed to fully complete the chemical reaction. Stoichiometry is the relationship between the quantities of the reactants. An acid is a substance that reacts and donates H+ ions. A base is a substance that accepts H+ ions. An acid that donates more that two H+ ions is polyprotic. In a reaction where an…
an SN1 reaction. The SN1 reaction took place with a polar protic solvent taking the place of the leaving group (alcohol) and creating a new replacement bond with the carbocation to form a tertiary chloride structure. The product was then tested for this structure by reacting it with two substances: sodium iodide and silver nitrate. These tests were to demonstrate that if the product obtained through experimentation was indeed a tertiary structure, it would react readily via an SN1 reaction with…