Phase 2 – Agarose Gel Electrophoresis 1. Obtain our four H, E, L, and P labeled micro tubes and place them on ice. 2. Set the micro pipet to 2.0 ul. 3. Transfer 2.0 ul blue dye to each of the four H, E, L, and P micro tubes. 4. Mix the four micro tubes by using this two-step method: * Place each tube briefly on the vortex to get the components to collect at the bottom of the micro tubes * Pulse spin the four micro tubes in the centrifuge to mix all of the components completely. 5.…
1.4 Effect of Microcrystalline Cellulose (MCC)Type Formula F12 was utilized to study the effect of changing the type of MCC(Avecil PH-101 ) as a carrier material instead of (Avecil PH-102) in F8 on the dissolution behavior of the prepared Zolmitriptan liquisolid ODTs. Although the DT of formula F12 (79 sec.) was greater than F8 (48 sec.) as in Table(18),the dissolution behavior of the formula F12 was faster than F8 as in Table (18) and Figure (48), this difference was non…
According to R.A Aitken, “An asymmetric synthesis may be defined as a synthesis in which an achiral unit is an ensemble of substrate molecules is converted to a chiral unit such that the possible stereoisomers are formed in unequal amounts.” It relates to any synthetic process that incorporates one or more new elements of chirality during a functional group transformation. Asymmetric synthesis involves the formation of chiral molecules. An object is said to be chiral, if it cannot be…
Background : Stoichiometry is the relationship between the relative quantities of substances taking part in a reaction or forming a compound, typically a ratio of whole integers. In the lab that I did with my group we used stoichiometry to find out the decomposition of sodium biocarbonate. Sodium carbonate is just another name for baking soda, and that is what we used on our lab. Baking soda is also used in some food items, such as pancakes, waffles etc… When the baking soda is being heated…
You can choose different percentage of chemical composition and control, and adapt it to the various requirements of the product. Mild steel has good weld-ability and machine-ability. The weight of Mild steel is much less when compared to Iron.…
and DSC analysis. The solubility revise in aqueous system showed an improvement within the solubility of conjugates. The dissolution studies showed an accurate acid–base catalysis prototype reliant on the pH of the medium. This indicated a fine chemical constancy in aqueous buffer solution of acidic medium and the comprehensive discharge performance was found in prodrug…
Diels-Alder Reaction Objective: The objective of this lab was to do a diels-alder reaction using anthracene, maleic anhydride, and xylene to create 9,10-dihydroanthracene, 10-, -succinic acid anhydride. Experimental: Anthracene (1.00g, 5.61x 10-3 mol), maleic anhydride (0.75g, 7.61x 10-3 mol), xylene (5mL, 4.71x 10-2 mol), and a stir rod were added into a round-bottomed flask. The round-bottom flask was then moved to the hood where the it was attached to a distillation column, placed on…
INTRODUCTION Conformational isomerism is a type of stereoisomerism whereby the isomers are interconverted by rotations about the single bonds. There be terms used below such as eclipsed conformation, staggered conformation,dihedral angle and a few more. Eclipsed conformation is the conformation whereby the C-H bonds on one carbon is directly aligned with the C-H bonds of the adjacent carbon. When the C-H bond of one carbon bisects the H-C-H bond on the adjacent carbon, it is known as staggered…
Since suitable crystals for X-ray single crystal analysis was not obtained, to have reliable structural information, HR-TEM analysis of the product was carried out. The average size of the assembly calculated from HR-TEM measurement is found to be 2.8 nm which is in good agreement with the size of the previously reported Pd6L8 assembly where L is the non N-methylated (2.5nm, Fig. 2).9 As first step, to explore the catalytic activity of 1 in copper and phosphine free Sonogashira coupling reaction…
New method of synthesis of oligoetherols with carbazole ring Renata Lubczak Abstract: The new method of synthesis of multifuntional oligoetherols with carbazole ring suitable for obtaining the polyurethane foams of enhanced thermal resistance was presented. At the first step of the synthesis the carbazole was reacted with excess glycidol to obtain the product of (n +1) functionality, where n is number of equivalents of glycidol reacted with carbazole. Carbazole reacts with glycidol without…