Asthma and chronic obstructive pulmonary disease (COPD) are among the most common and prevalent diseases in the world (Raadhika and Shanthi, 2012; Rao and Kulkarni , 2012). Salbutamol sulphate (SS) is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm (Sharma et al., 2015). Salbutamol sulphate is readily absorbed from the gastro intestinal tract following oral administration, and it undergoes the first pass metabolism in the liver. It requires multiple dosing a day…