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    KRAS Case Study

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    bound and active GTP bound forms & are critical for cell proliferation, Survival & differentiation. Ras can activate downstream effectors including PI3K-AKT-mTOR and RAS-RAF-MEK-ERK…

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    Anton Cancer: A Case Study

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    (Demain 1981). These micro organism live in a highly diverse environment ranging from hot springs to deep ocean sediments. In the hyper diverse environment where one can find a specialized and unique biological niche is the intracellular space between cells of higher plants acts as suite and supports the growth of microbes and the one which grows there is called as endophytes (Strobel and Daisy 2003).  Endophytes The word endophyte literally means “In the plant” (Gr. endon = within; phyton =…

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    Prokaryotes There are two types of organisms based cell types: Prokaryotic and Eukaryotic. Prokaryotic cells are divided into two parts: Bacteria and Archaea. Prokaryotes are much smaller than eukaryotes. Prokaryotes contain a single loop of chromosomal DNA which is stored in nucleoid. Eukaryotes DNA is found on tightly bound and organised chromosomes. Genetic expression is the process where genotypes coded in the genes are displayed by the phenotypes of the individuals. The DNA is then copied…

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    1. Francis Crick Crick discovered the relative distances of the repetitive elements in the DNA molecule, and the dimensions of the monoclinic unit cell which indicated that the molecule was in two matching parts, running in opposite directions. He also, in collaboration with Watson discovered the material that our genes are made of and put forward the model of the double helix DNA structure which included the measurements of the angels formed by different chemical bonds. Crick in collaboration…

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    bases that happen successively (Weinhold, 2006). It is a profoundly specific process that consistently happens in areas that a cytosine nucleotide is situated beside a guanine nucleotide, which is connected to a phosphate. This is better known as a CpG site, which is methylated by chemicals called DNA methyltransferases. By introducing methyl groups, it makes the structure and the appearance of the DNA change without really adjusting the DNA arrangement. Simmons stated that sometimes in some…

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    Dna Synthesis

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    daughter strands of DNA have been produced, it is time to proofread and repair the DNA sequence. This process is so important because any mistake in DNA replication can result to DNA mutation and will lead to various genetic diseases such as sickle cell anaemia, Huntington’s disease and many more (Cooper, 2000). Thus, the accuracy of DNA replication cannot be attributed solely to the specificity of the base pairing. According to Khan Academy (2017), to avert the mistake from happening, an enzyme…

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    The Central Dogma

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    Introduction Information processing is crucial in all fields of science. In molecular biology, the central dogma, first devised by Francis Crick, is a classical backbone of living cells to essentially perform the processes from cell division to death through the DNA, RNA, and protein information ways. More specifically, the central dogma defines the transfer of sequence information during DNA replication, transcription into RNA, and translation into amino-acid chains forming proteins. It also…

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    It is well known that all organisms require at least some water to survive, even the most hardy creature on the planet earth, the tardigrade, Hypsibius dujardini, which can survive near complete dehydration, exposure to extreme radiation, vacuum, temperature and pressure, must be rejuvenated with water if it is to resume life after near complete desiccation (Gabriel, et al. 2007). H. dujardini, famous for surviving some of the harshest conditions of any organism we know of, is a perfect example…

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    stage, the caterpillar starts to grow rapidly and totally rebuilt by differentiating into different tissues. Once the caterpillar reach its maximum size until it looks like a giant droplet, it change behaviour and stop feeding and begin to create a site for pupation. This process are rapidly occur and last for two to three weeks or prolonge that last more than a year. Brower (2007) noted, that inside the fifth instar, the hormonal changes take place by losely all it interest in feeding. The…

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    Lab #5 Assignment: Protein Analysis by SDS-PAGE Introduction: Different cells and tissues express different proteins because of gene expression. Gene basically reflects what the protein will be and also its function. The expression must be controlled by some kind of regulation in the processes of transcription and translation. For example, in transcription, enhancer sequences provide binding sites for regulatory proteins that will affect RNA polymerase activity. On a related note, the size of…

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