ABSTRACT Dex-Ibuprofen–polyethylene glycol (PEG) conjugates (PEG-dex-Ibu) were organized and their prospective as a prolonged release method was investigated. PEG-Dex-Ibuprofen conjugates were synthesized as of Ibuprofen and PEG with 4000 Da molecular weights by esterification in the incidence of DCC and DMAP. The PEG-dex-Ibu conjugates were characterized by FT-IR, 1H NMR, and DSC analysis. The solubility revise in aqueous system showed an improvement within the solubility of conjugates. The…
malondialdehyde (MDA) level as one of the main end products of lipid peroxidation (Yoshioka et al., 1979), reduced glutathione (GSH) content (Beutler et al., 1963), superoxide dismutase (SOD) (SOD assay kit, Sigma-Aldrich Co, St Louis, MO, USA) and catalase (CAT) activities (Sinha, 1972). 2.7. Assessment of cardiac inflammation Sera were used to estimate TNF-α concentration using commercially available ELISA kit (Boster Biological Technology, Pleasanton, CA, USA) while Myeloperoxidase (MPO)…
Introduction Cat scratch disease is an infection caused by the bacterium Bartonella henselae. As the name of the disease implies, it is associated with a scratch from an infected cat but is also transmitted through a cat bite and, in some instances, cat fleas (Forbes, 2007). The formation of a papule at the site of the bite or scratch is the initial symptom followed by lymphadenopathy. One of the most common causes of chronic lymphadenopathy in children and adolescents is cat scratch disease…
Methods There are many important factors to any experiment, including the materials. To continue, the quantity of materials for this experiment varies from a refrigerator to tweezers, but they all need to be included for the best results. First, the larger materials needed to complete the experiment are refrigerator, freezer, stove, one ice box, one scale which could be large or small, one blender, one cooking pot, one large jar or cup, and at least 400 milliliters of distilled water. Next, the…
Introduction Gardnerella Vaginalis also known as Bacterial Vaginosis is a bacterial infection normally found in the female’s genital tract [5]. This can cause a female to go through abnormal vaginal odor and discharge. Generally an unpleasant fishy smell with a yellow or white discharge [2]. Garnerella Vaginalis otherwise Bacterial Vaginosis can be contracted through vaginal douching, multiple or new sex partners and intrauterine contraceptive device (IUD). Bacterial Vaginosis is not only…
Chemistry Lab Report NAME: Serina Alashi DATE: TITLE: Decomposition reaction: hydrogen peroxide (H2O2) decomposed into hydrogen and oxygen ( H2 and O2) RESEARCH QUESTION: How will changing the concentration of hydrogen peroxide affect the rate of reaction, that is represented by the increase in pressure over time? Introduction: Hydrogen peroxide is a chemical compound of hydrogen and oxygen. It is a very strong oxidant but weak in water solution. Hydrogen peroxide decomposes into water…
Experimental trials were performed by students over a timeframe of three weeks to determine the identity of three unknown bacteria contained in broth medium stored in labeled test tubes that were randomly assigned containing: one Gram positive bacterium, one Gram-negative paracolon, and one Gram-negative coliform (Carson, 2016). The unknown sample assigned in this experiment was #19. After initially streaking the solution on clean streak plates and TSA agar, the identity was determined from a…
Anthony Alvarado Bio 1A Chronic oxidative stress via hydroxyl radical and imbalanced redox homeostasis Redox hemostasis has been shown to be an important factor in the overall aging and neurodegeneration processes in mammalian models; such as, Alzheimer’s and Parkinson’s. As a result, redox homeostasis has been a key point of interest in current research. Redox homeostasis is the balance between electrophiles and nucleophiles in a system, more importantly in a biological system. These…
CHAPTER THREE MATERIAL AND METHODS 1. PHYSICO-CHEMICAL CHARACTERCITICS: The effluent collected were analyzed in the laboratory for pH, acidity, alkalinity, salinity, total dissolved solid(TDS), conductivity, total hardness, calcium hardness, magnesium hardness, total solid, total suspension solid, turbidity, BOD, DO and COD using standard methods (APHA,2005). A.DETERMINATION OF pH: The electrode of pH meter was calibrated with standard buffer solutions of pH 4, 7 and 9. The electrode was then…
F214 Communication, Homeostasis and Energy Module 2 Excretion 4.2.1 Excretion a. Define the term excretion Excretion-The removal of metabolic waste from the body which are by products or unwanted substances from cell processes. b. Explain the importance of removing metabolic wastes, including carbon dioxide and nitrogenous waste from the body Carbon dioxide Excess carbon dioxide is toxic and has three main effects: The majority of carbon dioxide is carried in the blood as…