Ever since the discovery of recurrent gene fusions in prostate cancer in 20053, several prostate cancer specific molecular aberrations have been identified and are potentially targetable with specific inhibitors (Figure 1). Despite the high prevalence, the clinical utility and association of these markers with disease progression has not been firmly established. It may be due to the fact that the estimates on the prevalence of these molecular markers and clinical correlation analyses were based…
high osmolality causing erythrocyte dehydration. The consequent vaso-occlusion causes renal infarction with papillary necrosis, and medullary fibrosis with focal segmental glomerulosclerosis. Other complications include haematuria, renal medullary carcinoma, nocturnal enuresis (bedwetting), and chronic tubulointerstitial nephritis may occur. Neurological complications Complications occur in 25% of patients, Sickle-cell anaemia is one of the most common causes of stroke in children. Most cases…
sunscreen’s role Most cancer rates are decreasing, whereas skin cancer continues to steadily increase as it has for the past decades (Saraiya et al. 422). The three most common skin cancers are squamous-cell, basal-cell and melanoma carcinomas. Squamous-cell and basal-cell carcinomas are grouped as non-melanoma cancers. Family history and genetic disorders increases the risk of forming cancer; however, estimates place excessive sun exposure as causing as much as 90% of all melanoma diagnosis…
colon cancer, prostate cancer, ovarian cancer, and breast cancer combined. Cancer is an ancient disease. Mummies, some even 2,500 years old, were discovered in Peru with lumps that clearly suggest cancer as the cause of death . Lung cancer is the carcinoma that affects the lungs, which is the abnormal growth starts in the epithelial cells that line the bronchial tubes and the alveoli. The roles are to draw oxygen from the air that the cells need to stay alive and expel the…
of anal glands is thought to be the partial reason. The infected gland leads to fistula formation after some time, which starts as an abscess. There are, of course, other causes include chronic ulcerative colitis, Crohn's disease, tuberculosis, carcinoma of the rectum or anal canal, benign rectal strictures, foreign bodies or diverticulitis. Parks at el explicate the primary tracts as following four…
lump. Breast cancer is more common in women than men are, but they also need to realize that they can also be diagnosed with breast cancer. Fibro adenoma has been identified as the most prevalent form of benign breast tumor, while Invasive Ductal Carcinoma is the prevalent kind of malignant breast tumor. Statistics illustrate that breast cancer is more likely to be found on older women who are fifty years and above, but there has been a swing of events where younger women who are below fifty…
Diseases and Disorders of the Integumentary, Skeletal and Muscular, Systems BY: ANTHONY SALEM Integumentary System The Integumentary System is composed of Skin and accessory Organs such as hair, nails, and Cutaneous Glands Largest Organ! Skin weighs about six pounds and sheds every 27 days Integumentary Cont. Functions of skin • Works to waterproof body (Keratin, a fibrous protein aids in this) • Acts as a cushion and protects body from infection • Excretes waste • Regulates…
The patented invention is Sorafenib Tosylate (ST), a palliative medicine for hepato-cellular carcinoma and renal cell carcinoma and affects a very small percentage of the population (Kurian 2011, p. 13351). The drug is administered only on prescription and supervision of oncologists and the patients are at stage IV of the disease and the drug admittedly improves the quality of life in the last months of the afflicted ones. CL is one of the major flexibilities allowed under the WTO agreement on…
Most tumors of parathyroid glands are benign lesions, involving one or multiple parathyroid glands. Parathyroid benign tumors-related morbidity comes from PTH inappropriate and uncontrolled release. Similarly to other human cancers, parathyroid carcinomas (PCas) display local vascular and tissue invasiveness as well as…
To completely understand the US’s high standards, it is necessary to look at a real life US breast cancer survivor story. Darrelleen Lewis was diagnosed August 6, 2013 with stage 1 Invasive Ductal Carcinoma (IDC), which is the most common type of breast cancer in the US. She said that the cancer was found on a mammography and that was a biopsy was necessary to determine what exactly the spot was. Darrelleen received a called from her nurse giving her the terrifying news that she had breast…