Carbonyl

Rufinamide (Banzel) was designated as an orphan drug for use in the treatment of seizures that are caused by Lennox—Gastaut syndrome in patients older than four in 2004 by the FDA (Food and Drug Adminsitration).¬¬¬¬¬1 Lennox—Gastaut syndrome (LGS) is a epileptic disease, commonly found in children, that is characterized a high rate of injury from seizures as well as a wide range of treatment-resistant seizures. In the past treatments were inadequate, leaving patients without much, but after the…

2.1. C. tomentosum extract characterization C. tomentosum extract proximal composition is shown in Table 1. The relatively higher ash proportion in seaweed extract (SE) (aprox. 74%) could largely be accounted for by the lower moisture content, and probably due to a hygroscopic nature of the SE (Blanco-Pascual, Montero, & Gómez-Guillén, 2014). The values of TPC and DPPH radical-scavenging activity are consistent with literature (Andrade et al., 2013; Valentão et al., 2010) (Table 1). POD and PPO…

In the experiment, a Fischer Esterification reaction took place in order to convert a carboxylic acid into an ester. As a result of this reaction, the alcohol (-OH) of the original carboxylic acid, Benzoic Acid, will be replaced with the –OCH3 group attached to the original alcohol, methanol. This would then generate the ester, Methyl Benzoate. An ester is a derivative of a carboxylic acid that can be formed in multiple ways. The most straightforward approach to producing and ester involves the…

The resistive component of analysis can also be modeled as a spring in which the spring constant is positively correlated to the force applied to the spring: F= kx, where k = f(x)*Fimpact. The force of impact would mostly dissipate through the springs, and the specific behavior of the springs can be modeled in later stages. The component of force that needs to be looked at primarily is the x component, since this is the component of the force that would produce the most torque on collision.…

Calcium is the richest mineral in our body holding many functions during the human development. Ca2+ controls many cellular processes such as: metabolism, gene transcription, fertilisation, proliferation, hypertrophy, secretion, exocytosis, cardiac ventricular mechanisms, neuronal dopaminergic pacemaker mechanisms, contraction, coordination and thinking, (Rubin, 2016). These processes can occur anywhere between a few microseconds to hours to complete. The basal Ca2+ concentration of…

FDE 310 Food Materials Laboratory Report Determination of Reducing Sugar Content INTRODUCTION The objectives of this experiment is to determine reducing sugar content of food sample by performing Fehling method and to identify invert sugar content of sugars by using polarimetry and also to learn property of invert and reducing sugar. Carbohydrases represent a large class…

Methods Each trial consisted of isolating the hearts of two mice, aged anywhere between 8-15 weeks, with the strain FVB/NJ of the Mus genus. Eight trials were conducted throughout the duration of the experiment. No female mice were used for any of the trials because because the research in the lab concentrates on males, due to known differences in protein expression among the two sexes. The effect of the VU591 drug on mitochondrial KATP function in wildtype mice was measured by calculating the…

Introduction Food is the first of the essentials of life, the world’s largest industry, our most frequently indulged pleasure, the core of most intimate social relationship (1). Food identifies who we are, where we came from, and what we want to be (1). Food is composed of many complex molecules (2). Some provide structural components, some provide energy, some interact with various receptors and transmit signals to our bodies, and some are relatively inert (2). People sometimes oversimply food…

For the next two weeks, the objective of this lab is to explore EAS reactions. These reactions are possible spots on a benzene ring for substituting electrophiles due to compounds that are already on the ring. There are three types of directing substituents. The first one is a para-director which guides the second substituent on the opposite side of the benzene ring. The second director, which corresponds with para-directors, is the ortho-director. These directors place the group of atoms on the…

According to R.A Aitken, “An asymmetric synthesis may be defined as a synthesis in which an achiral unit is an ensemble of substrate molecules is converted to a chiral unit such that the possible stereoisomers are formed in unequal amounts.” It relates to any synthetic process that incorporates one or more new elements of chirality during a functional group transformation. Asymmetric synthesis involves the formation of chiral molecules. An object is said to be chiral, if it cannot be…