Calorimeter

role of various factors including chemical additives. It was necessary to come up with a list of learning objectives a few weeks after starting my co-op position. I decided it would be beneficial to gain an understanding of Differential Scanning Calorimeter (DSC), Thermogravimetric analysts (TGA) and…

How to Win Friends & Influence People Section One Principle: “Don’t criticize, condemn or complain.” Certainly, criticizing others is something that every person has been guilty of at some point or another. Why go through the time and effort to understand another person’s perspective when one can simply point out perceived flaws in that perspective? Dale Carnegie asserts, “Instead of condemning people, let’s try to understand them. Let’s try to figure out why they do what they do” (Carnegie,…

ABSTRACT Dex-Ibuprofen–polyethylene glycol (PEG) conjugates (PEG-dex-Ibu) were organized and their prospective as a prolonged release method was investigated. PEG-Dex-Ibuprofen conjugates were synthesized as of Ibuprofen and PEG with 4000 Da molecular weights by esterification in the incidence of DCC and DMAP. The PEG-dex-Ibu conjugates were characterized by FT-IR, 1H NMR, and DSC analysis. The solubility revise in aqueous system showed an improvement within the solubility of conjugates. The…

PRE FORMULATION STUDY: Pre formulation testing was an investigation of physical and chemical properties of a drug substance alone and when combined with excipients. It was the first step in the rational development of dosage forms. Class: -Pre formulation study can divide into two subclasses: API characterization, Compatibility study Active pharmaceutical ingredient (API) characterization:- Organoleptic evaluation:-These are preliminary characteristics of any substance which is useful in…

1. Materials and suppliers • Caffeine (anhydrous), BASF, Germany, was generously donated by Dar Al Dawa Development and Investment Company. Caffeine is 1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione. It is white or almost white, crystalline powder or silky crystals. It is sparingly soluble in water, freely soluble in boiling water and slightly soluble in ethanol. It is used as central nervous system stimulant (British Pharmacopoeia 2009). • Methyl paraben was generously donated by Arab…

• The heat (q) “lost” or “gained” is related to a) sample mass b) change in T and c) specific heat capacity Specific heat capacity = heat lost or gained by substance (J) (mass, g)(T change, K) © 2006 Brooks/Cole - Thomson 11 Change in Temperature (T) ∆T of System Increase Sign of ∆Tsystem + Tfinal >Tinitial Tfinal < Tinitial Sign of q + Direction of Heat Transfer Heat transferred from surroundings to system (_____thermic) Heat transferred from system to surroundings (_____thermic)…

CRISPR stand for: Clustered Regularly Interspaced Short Palindromic Repeat. The CRISPR is repeat spacer array contain a series of short direct repeats interspaced with short sequence which had been detected in the genome of many bacteria and archaea. The CRISPR method is based on the natural defense system used by bacteria to protect themselves from invading viruses. When the DNA of virus detected by bacterium, the CRISPR RNA as a guide RNA which contain a sequence, match to the invading virus…

To meet the ever increasing demands for improved quality of life, a number of pharmaceutical researchers have developed a variety of dosage forms and the oral route has always been the most preferred means of drug administration due to the ease, high patient compliance and low cost of production. In spite of a variety of dosage forms, tablets are most commonly adopted dosage form. The class II drugs have low solubility issues which results in poor dissolution rate and bioavailability[1,2].…

III. RESULTS AND DISCUSSIONS: A. Characteristics of Aluminum-Graphite composites and the in-situ reaction To examine the reaction condition of carbon flakes and Al powders, 4 wt. % carbon flakes were added to Al powders. Fig. 1 shows the DSC plot obtained during heating and cooling of the green compact from room temperature to 750 0C and from 750 0C to room temperature at a heating/cooling rate of 3 0C /min under argon gas atmosphere. From the DSC heating curve it is evident that the total…

What is meant by the specific heat capacity of a substance? It is the amount of energy required to increase the temperature of one gram of a body by one Kelvin unit, expressed as J/K/g. The specific heat capacity also can be measured in J/K/Kg and J/K/mol. Substance Specific heat Capacity (J/K/g) Water 4.18 acetone 2.17 hexane 2.26 Compare the specific heat capacity of water with a range of other solvents. The table compares the heat capacities of water and two other solvents. Compare the…