Breast cancer

APC is a tumor repressor and essential a cell growth regulator. It inhibits uncontrolled growth of cells which may lead to cancer. Mutations of APC often lead to colorectal cancer. Small polyps, which are the overgrown cells, appear in the colon and later lead to malignancy. APC regulates how often the cell divides, the cell’s attachment the cells within a tissues, the morphogenesis of the cell’s 3D structures, and how the cell polarizes. In addition, the proteins check to make sure the number…

Gabby Manupelli 3-15-16 Dear diary, For this month's disease diary, I found a disease that kind of interested me on a website with a list of almost every disease/disorder. The disease I found interesting was progesterone dermatitis. Since I had never heard of it before and it seemed interesting, I did some research. Progesterone dermatitis is a skin condition that is rare. This is a disease that can only be found in women. It is also known as autoimmune progesterone dermatitis. In this disease…

The results of deletions of Pix, Git, Fat, and expanded on the D. Melanogaster’s eyes and wings showed how disruption of these proteins affected the Hippo (Hpo) pathway and ultimately growth regulation. Following these results, what effects on cell growth would happen if Hpo was mutated so that it could not function was tested. To do this, wild type fly eyes were compared to flies that exhibited the HpoMGH1 mutation. The results showed that the flies in which Hpo exhibited loss of function…

Why do we need to be aware of heart disease in women? Heart disease is normally thought of as a “men’s disease”; however, statistically women are affected as much as men are. Signs and symptoms in women are not necessarily the classic symptoms of chest pain. Many women experience no signs or symptoms until they have heart failure, irregular heartbeat, or a heart attack (National Heart, Lung, and Blood Institute [NIH], 2014a). Heart disease is the leading cause of death in women, affecting…

Background: Oral squamous cell carcinoma is a challenging oncology problem. A reliable biomarker for invasion and metastasis in oral cancer patients remains to be more clarified. β-catenin acts as a structural protein at cell-cell adherence junctions and as a transcription activator mediating Wnt signal transduction. Altered β-catenin expression has been associated with loss of cell differentiation and acquisition of an invasive phenotype. Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is an…

Cancer, Lysosomes, and Treatment Cancer is one of the most leading causes of death across the world. Several therapies exist to fight cancer. They include surgery, radiation therapy, stem cell transplant, targeted therapy, hormone therapy, and immunotherapy. One common therapy many chose is chemotherapy. Chemotherapy is cancer treatment using one or more anti-cancer medications that are given as a standardized regimen. There are several types of chemotherapy medications. Alkylating agents attack…

The causes of cancer are observed as multifactorial. This is because there are several traits causing cancer such as genetic, environmental, medical and lifestyle factors. However the knowledge of cancer is rapidly improving, helping everyone to understand and be able to identify at risk individuals, tailoring treatment and developing new methods against cancer.(cancer.gov,2015) Genetic information includes information about an individual’s genes including the manifestation of a disease in the…

I would like to share a story that is very meaningful to me. I am a brain tumor survivor! One day when I was just four years old, my mom and I were sitting beside each other at the kitchen table coloring as we usually did. This time my mom noticed as she looked over at me that my profile had changed drastically. The bridge of my nose appeared to be completely flattened. In her words as I've heard the story so many times, "her profile had changed completely and it looked as though her nose had…

Cancer is an increasing and growing problem that is occurring all around us. Having a tremendous effect, cancer hits several people daily, which includes a close friend, relative, or parent. Reasonably necessary, my approach in promoting this issue for the job of Miss Georgia would be brilliant and intuitive. From experiencing the pain and agony it causes, I am currently a daughter of a victim. Cancer is deadly, and it doesn’t heal quickly. Promoting this issue, I would share and heighten…

There are non-medical ways to treat cancer which has attracted a lot of new patients due to cost of treatment and research that shows a significant decrease in cancer symptoms. Alternative cancer treatments in the form of diets, exercise, meditation, and supposed remedies have been promoted by questionable sources for many decades (American Cancer Society, 2016). The non- medical method have not been proven to be effective at reducing, reversing, or killing cancer although many of the…