BRCA2

Technology is very important in human society and become inseparable with people’s life. There are still a huge number of people who begin to use technology every day and quickly increasing. Majority of people no matter in school or at work are using cellphone and laptop for wither class or work. The vitality of technology would give people different method of use and one of the most important function is communication. One of the most useful technology product “internet” is use to spread out…

Ovarian cancer is when cells begin to uncontrollably reproduce in the ovaries, and may spread to other parts of the body. It ranks number five in cancer deaths among women and accounts for more deaths than any other cancer of the reproductive systems of women. It starts in the ovaries and can spread to the rest of the body, giving the woman's lifetime chance of dying from the disease 1 in 100. This cancer mainly develops in older women- about half of the women who are diagnosed are over 63 years…

Breast cancer is the most common cancer and the second leading cause of cancer deaths in women in the United States. In 2008, approximately 184,450 patients were estimated to be diagnosed with invasive cancer, and an estimated 40,930 were estimated to die of this disease. Furthermore, over 50,000 female carcinoma in situ breast cases would have been diagnosed. The etiology of breast cancer is poorly understood with multiple genetic and environmental factors involved in the initiation and…

ROLE OF IMMUNOHISTOCHEMISTRY IN THE DIAGNOSIS OF SYNDROMIC GYNECOLOGICAL CANCERS Both ovarian and endometrial carcinomas can be expression of genetically inherited syndromes. Two main hereditary cancer syndromes are known that predispose to cancers occurring in the gynecological tract, namely Lynch and hereditary Breast and Ovary Cancer syndromes. Lynch syndrome is due to germline mutations in the MMR system, including MLH1, MSH2, MSH6 and PMS2 genes, and in EPCAM gene, that cause high…

Healthcare providers are faced with ethical dilemma every day. However, the Health Insurance Portability and Accountability Act (HIPPA) emphasizes on the ethical and legal value of confidentiality. While a provider has a duty to warning Rachel of the consequences the genetic testing information can have to her sister Kristin, the provider however, do not have a duty to breach Rachel’s confidentiality so as to warn Kristin directly. The obligation of the provider is to encourage Rachel to tell…

changes in the genes are influenced by lifestyle and environmental factors resulting to breast cancer. BRCA1 or BRCA2 are also a type of genes…

Expect Comments Live Date (AMY) URL (AMY) BRCA Testing BRCA testing is an important tool in the fight against breast cancer BRCA testing is designed to find mutations in two important genes that suppress cancer - the BRCA1 and BRCA2 genes. When BRCA1 and BRCA2 genes are unaltered, they produce proteins that suppress malignant tumors. If these genes are genetically altered, or mutated, they don’t work properly, putting a woman at higher risk for developing breast and ovarian cancers. Our…

Cancer refers to several diseases that the involve uncontrolled growth of mutated cells in the body. Normally, cells grow and divide based on signals and the body’s needs, and new cells replace old or damaged cells. However, cancer is able to develop when cell signaling is interrupted. The old cells stop dying and instead form new abnormal cells, possibly resulting in a tumor. Cancerous cells are malignant, which means they can invade nearby tissue, and can potentially metastasize and spread to…

(Breast Cancer Gene One) and BRCA2 (Breast Cancer Gene Two). BRCA1 and BRCA2 are present in everyone. BRCA genes are help to keep breast cells work properly and to repair the cell damage .When these genes do not function properly due to mutation in these genes are passed from one generation to another, the chances of breast cancer increases .Breast cancer susceptibility is a complex process in which multiple genes may involved .Breast cancer linked with abnormal BRCA1 and BRCA2 are developed in…

mutations and breast cancer. Breast cancer can be hereditary, however, the probability that a lady develops cancer through inheritance of a penetrant cancer gene validates the need for predictive cancer testing. The tests target genes such as BRCA1, BRCA2…