Difficult neuropathy is a typical, and on occasion crippling, inconvenience of diabetes. Roughly one out of four individuals with diabetes might be influenced by interminable neuropathic torment. Patients frequently give inconvenience, normally beginning in the distal feet, yet advancing proximally after some time. Patients may depict manifestations of deadness, shivering, consuming, hurting, electric stuns, or lancinating torments .Other locales that are frequently influenced incorporate the…
stools) can lead to weight loss. Also some people get anemia because of low iron cells cause or lost by the bloody stools or intestinal inflammation. My aunt had all of the above symptoms; this is why she had to follow up with her doctor to check her blood counts every two…
Famous historical figures such as King George III of England and Vincent van Goh were thought to have been affected by porphyria. The term porphyria is derived from the ancient Greek word ‘porphyra’ which means purple, which is the colour of porphyrins that are known to cause the disease. B.J. Stokvis is the first known to have clinically described acute porphyria in 1889. The first type of porphyria to be described is acute intermittent porphyria (AIP), and will also be the focus of this…
Sprague Dawley rats (male, 9 weeks, 180-200 g) were obtained from the Vital River Co., Ltd (Beijing, China) and maintained at controlled temperature (22±2°C) and humidity (50±10%) with a 12h light/ dark cycle. All efforts were made to minimize the pain of animals. The experimental protocol was approved by the Ethics Committee of Beijing University of Chinese Medicine (No.: Kj-dw-18-20150821-01). 2.3 Chronic Restraint Stress After seven days of acclimatization, rats were divided into five groups…
Diabetes Mellitus Type 2 is a complex chronic metabolic disorder characterised by increased insulin resistance and impaired insulin secretion by pancreatic beta cells and involving an interplay of various genetic and environmental factors. This report discusses the pathogenesis and long term complications of type 2 diabetes as well as several pharmacological treatments. Pathogenesis of Type 2 Diabetes Genetic predisposition contributes to the pathogenesis of Type 2 diabetes as evidenced by a…
Question: The year is 2020. You are a postdoc currently working on a randomized control trial evaluating the influence of whole fat vs. low fat dairy products on cardiometabolic risk factors. Part of your analysis includes a blood test for a variety of compounds (e.g., minerals and hormones). As you sift through the data, you come across an unusual result: one subject has abnormally high calcium plasma levels. Upon further investigation, you find that their parathyroid hormone (PTH) plasma…
Are you experiencing a painful bump on the side or top of your toes? This is typically known as a corn and can cause discomfort. Hartford Podiatry Group, located in Rocky Hill, has experience in a wide array of foot conditions and problems, including bunion surgery, heel pain, and ingrown toenails. When it comes to the prevention and treatment of Corns, they are some of the best podiatrists that Connecticut has to offer. They’ve contributed some further information on corns, and when individuals…
Hormones and the Ketogenic Diet Ketogenic diet has a direct effect on the level of two important hormones, first is insulin and second is glucagon. On studying the nature of insulin, it is found that insulin is a type of hormone, which is responsible for transporting nutrients to the targeted tissues, by separating the nutrients from the bloodstream. For exam- ple, muscle stores glucose, which becomes glycogen and adipose tissue stores FFA which becomes triglycerides and this is all due to…
a group of different diagnoses. They are PreDiabetes, Type 1 Diabetes, Type 2 Diabetes, and Gestational Diabetes. PreDiabetes is exactly what the name implies. It is the precursor to Type 2. PreDiabetes is simply when your glucose levels in your blood are abnormally high. There are no symptoms purely for this diagnosis, but some people experience a few of the symptoms of other types. Just because one is diagnosed with PreDiabetes doesn’t mean that Type 2 will follow. With PreDiabetes as there…
It is estimated that nearly 35% of the US population has metabolic syndrome1. Metabolic syndrome encompasses a cluster of disorders that increase risk of cardiovascular disease and type 2 diabetes.2 The GI tract is home to trillions of microorganisms that confer benefits to the host. Recent evidence has implicated alternations in gut microbiota composition and metabolic activity in the pathophysiology of metabolic syndrome3,4. Maintenance of gut barrier function, regulation of immune response…