Blood-brain barrier

vasculature, and for years, the theory of the nonexistence of the lymphatic system in the brain has been accepted as a biological/anatomical fact. This very basic fact of neuro-anatomy has recently been upset by two independent studies, revealing that the brain does, in fact, have a functional lymphatic system. Although this study was originally done on mice brains, there have been similar findings in human cadaver brains. We know that the lymphatic system provides the body with a waste disposal…

strands called tangles. The tracks cannot stay straight and nutrients and other materials cannot reach the neurons. These cells eventually die due to a lack of nutrients (Alzheimer’s Disease & Dementia). Tau is the protein involved in tangles in the brain and tau aggregation inhibitors and tau vaccines are being researched for future treatment for people with Alzheimer’s. Hopefully these drugs will stop tau from forming…

is a group of cells, in the nervous tissue that supports neurons that keeps the nervous system functioning and together. The 4 types of neuroglis cells of the CNS: (1.) Astrocytes are cells that support and structure cells that is a barrier for the brain through blood. (2.) Microglial cells are cells that remove dirt and attack microbes. (3.) Ependymal cells are cells that covers and lines the surfaces and cavities. (4.) Oligodendrocytes are cells that makes myelin that holds the nerve fibers in…

system is really important because it’s in charge of sending messages to the spinal cord and brain to and from all parts of the body. Main organs of the nervous system are Nervous Tissue, Brain, Spinal Cord, Nerves, Sense Organs, and the Cerebrospinal Fluid. The nervous tissue is the main tissue of the central and peripheral nervous system. This tissue conducts nerve impulses and is composed of neurons. The brain sends messages to the spinal cord the peripheral nerves all over the body that…

their delivery to the tumor site. Perhaps the biggest obstacle is the localization of tumors in the brain, which implies that the anti-cancer agent must be able to penetrate the blood brain barrier (BBB). The BBB is a highly selective permeability barrier that separates circulating blood from cerebrospinal fluid in the Central Nervous System (CNS). It is mainly formed by endothelial cells lining the brain microvessels. Pericytes envelope a part of the endothelium and have a common basal lamina.…

Carlson (2014) the Nervous system is branched into two categories - the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is made up of the brain and spinal cord. The PNS holds cranial nerves, spinal nerves and peripheral ganglia. According to Farley, Johnstone, Hendrey and McLafferty (2014), the brain is portioned into six different sections. These divisions consist of the medulla oblongata, pons, midbrain, cerebellum, diencephalon, cerebrum. According to James W.…

There is aggressive competition to be seen in this industry as this industry has been around for a relatively long time. Rivalry occurs because competitors will either feel the peer pressure or seeing growing in opportunity of the business. The potential competition can be seen from sustainable innovation competitive advantage, price competitions and corporate strategy (Cafferky, 2015). The rivalry between the furniture retailers is viewed as medium to high threat as competitors have been…

Industry environment analysis Threat of new entrants Established businesses are protected from new entrants because of high barriers to enter the market. New entrants will face barriers such as high product differentiation, high capital requirements, economies of scale, switching costs, access to distribution channels, government policies and threat of retaliation (see appendix C) (Gheen et al., 2012). Bargaining power of suppliers The suppliers of the apparel industry are reliant on one major…

External Analysis: Michael Porter’s five forces In business the ability to make profit depends on how strong of a position the company has in the market. This is determined by; how many competitors that offer the same products, how easy is it for other companies to enter the market if they can see that you make a profit, and how dependent are you to your customers that leads them in to making you lower your price. It is essential to determine you’re positioning in order to avoid working very…

especially threatening when buyers can easily find substitute products with attractive prices or better quality and when buyers can switch from one product or service to another with little cost. 2. Threat of the entry of new competitors, such as barriers to entry (i.e.…